ZILOS-tk® and LYKOS® Articles

Below is a tabbed list of ZILOS-tk and LYKOS publications. If you would like a copy of any of the articles listed as "Available", please email webmaster [AT] hamiltonthorne [DOT] com. You may also download a PDF file of publication list.

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ZILOS-tk & LYKOS Publications by Year

Available? Citation Reference
No Awadalla MS, Park KE, Latack KR, McGinnis LK, Ahmady A, Paulson RJ. Influence of Trophectoderm Biopsy Prior to Frozen Blastocyst Transfer on Obstetrical Outcomes. Reproductive Sciences. 2021 March 25: [1p.]. doi: https://doi.org/10.1007/s43032-021-00552-z.
Yes Badeghiesh A, Konci R, Aldhaheri S, Son WY, Dahan MH. Effect of Double Embryo Transfer Derived from Autologous Frozen Oocytes on Multiple Pregnancy Rates and Presentation of Success Rates Stratified for Age at Retrieval Badeghiesh et al. Single vs. double ET with frozen oocytes. J Turk Ger Gynecol Assoc. 2021 June 10: 1-7. doi: 10.4274/jtgga.galenos.2021.2020.0207. Open Access Article
No Bellver J, Brandao P, Alegre L, Meseguer M. Blastocyst Formation is Similar in Obese and Normal Weight Women: a Morphokinetic Study. Human Reproduction. 2021 Oct 03:[1p.]. doi:https://doi.org/10.1093/humrep/deab212.
No
Chang D, Hu L, Gong F, Yuan S, Luo K, Wu X, Xie P, Lu C, Lu G, Tan YQ, Lin G. Clinical Outcomes Following Preimplantation Genetic Testing and Microdissecting Junction Region in Couples with Balanced Chromosome Rearrangement. J Assist Reprod Genet. 2021 Jan. 11: 1-8. doi:  https://doi.org/10.1007/s10815-020-02052-6 
No Fang S, McLean J, Shi L, Vink JSY, Hendon CP, Myers KM. Anisotropic Mechanical Properties of the Human Uterus Measured by Spherical Indentation. Annals of Biomedical Engineering. 2021 April 20: [1p.]. doi:https://doi.org/10.1007/s10439-021-02769-0.
No Hanigan MD, Souza VC, Martineau R, Daley VL, Kononoff P. Predicting Ruminally Undegraded and Microbial Protein Flows from the Rumen. Journal of Dairy Science. 2021 May 10: [1p.]. doi: https://doi.org/10.3168/jds.2020-19672.
No Hao Y, Long X, Kong F, Chen L, Chi H, Zhu X, Kuo Y, Zhu Y, Lin J, Yan L, Li R, Liu P, Wang Y, Qiao J. Maternal and Neonatal Outcomes Following Blastocyst Biopsy for Preimplantation Genetic Testing in Single Frozen-Thawed Embryo Transfer Cycles. Reproductive BioMedicine Online. 2021 July 29: [1p.]. doi:https://doi.org/10.1016/j.rbmo.2021.07.016.
Yes Hu J, Molinari E, Darmon S, Zhang L, Patrizio P, Barad DH, Gleicher N. Predictive Value of Cytoplasmic Granulation Patterns During In Vitro Fertilization in Metaphase II Oocytes: Part I, Poor-Prognosis Patients. Fertility and Sterility. 2021 April 15: 1-10. doi:https://doi.org/10.1016/j.fertnstert.2021.02.022. Open Access Article
No Jaswa EG, McCulloch CE, Simbulan R, Cedars MI, Rosen MP. Diminished Ovarian Reserve is Associated with Reduced Euploid Rates via Preimplantation Genetic Testing for Aneuploidy Independently from Age: Evidence for Concomitant Reduction in Oocyte Quality with Quantity. Fertility and Sterility. 2021 Feb. 12: [1p.]. doi: https://doi.org/10.1016/j.fertnstert.2020.10.051.
Yes Kaskar K. Optimizing Embryo Culture Conditions and Spent Culture Media Analysis as Predictors of Embryo Quality and Pregnancy [dissertation]. [Cape Town]: University of West Cape; 2021, 211p. Open Access Article
No Keskin M, Pabuccu EG, Arslanca T, Demirkiran OD, Pabuccu R. Does Microfluidic Sperm Sorting Affect Embryo Euploidy Rates in Couples with High Sperm DNA Fragmentation? Reproductive Endocrinology. Reproductive Sciences. 2021 Nov 03: [1p.]. doi:https://doi.org/10.1007/s43032-021-00784-z.
No Li X, Hao Y, Chen D, Ji D, Zhu W, Zhu X, Wei Z, Cao Y, Zhang Z, Zhou P. Non-invasive preimplantation genetic testing for putative mosaic blastocysts: a pilot study. Human Reproduction. 2021 July; 36(7): 2020-2034. doi: https://doi.org/10.1093/humrep/deab080.
Yes Mizobe Y, Kuwatsuru Y, Kuroki Y, Fukumoto Y, Tokudome M, Moewaki H, Watanabe M, Iwakawa T, Takeuchi K. A Novel Trophectoderm Biopsy Technique for All Blastocyst Stages. Reprod Med Biol. 2021 Sept 23; 00: 1-7. doi: 10.1002/rmb2.12418. Open Access Article
No Oliva M, Briton-Jones C, Gounko D, Lee JA, Copperman AB, Sekhon L. Factors Associated with Vitrification-Warming Survival in 6167 Euploid Blastocysts.J Assist Reprod Genet. 2021 July 26: [1p.]. doi:https://doi.org/10.1007/s10815-021-02284-0.
No Putnam JM, Zhang L, Gregg AR, Testa G, Johannesson L. Clinical Pregnancy Rates and Experience with In Vitro Fertilization After Uterus Transplantation: Dallas Uterus Transplant Study. American Journal of Obstetrics and Gynecology. 2021 March 12: [1p.]. doi:https://doi.org/10.1016/j.ajog.2021.02.037.
No Oliva M, Briton-Jones C, Gounko D, Lee JA, Copperman AB, Sekhon L. Factors Associated with Vitrification-Warming Survival in 6167 Euploid Blastocysts.J Assist Reprod Genet. 2021 July 26: [1p.]. doi:https://doi.org/10.1007/s10815-021-02284-0.
No Qu FSY, Weng SP, Shen MS, Ma PC, Wu PK, Lee NC. Suboptimal Trophectoderm Mitochondrial DNA Level is Associated with Delayed Blastocyst Development. J Assist Reprod and Genet. 2021 Jan. 20: [1p.]. doi: https://doi.org/10.1007/s10815-020-02045-5.
Yes Raeeszadeh M, Karimfar B, Amiri AA, Akbari A. Protective Effect of Nano-Vitamin C on Infertility due to Oxidative Stress Induced by Lead and Arsenic in Male Rats. Journal of Chemistry. 2021 Sept 30; 2021 (9589345): 1-9. doi:https://doi.org/10.1155/2021/9589345. Open Access Article
No Stovezky YR, Romanski PA, Bortoletto P, Spandorfer SD. Body Mass Index is Not Associated with Embryo Ploidy in Patients Undergoing In Vitro Fertilization with Preimplantation Genetic Testing. Fertility and Sterility. 2021 April 4: [1p.]. doi: https://doi.org/10.1016/j.fertnstert.2021.02.029.
Yes Wang Y, Chen C, Liang J, Fan L, Liu D, Zhang X, Liu F. A Comparison of the Clinical Effects of Thinning and Drilling on Laser-assisted Hatching. Lasers in Medical Science. 2021 Jan. 13: 1-9. doi: https://doi.org/10.1007/s10103-020-03230-9. Open Access Article
No Xiong S, Liu JX, Liu DY, Zhu JH, Hao XW, Wu LH, Gao Y, Li JY, Huang GN. Prolonged Interval Time Between Blastocyst Biopsy and Vitrification Compromised the Outcomes in Preimplantation Genetic Testing. Zygote. 2021 Feb. 18: 1-6. doi:10.1017/S0967199420000866.
Yes Xiong S, Liu W, Wang J, Liu J, Gao Y, Wu L, Zhu J, Hao X, Li J, Liu D, Han W, Huang G. Trophectoderm Biopsy Protocols May Impact the Rate of Mosaic Blastocysts in Cycles with Pre-implantation Genetic Testing for Aneuploidy. Journal of Assisted Reproduction and Genetics. 2021 March 4: [1p.]. doi:https://doi.org/10.1007/s10815-021-02137-w. Open Access Article
No Xu S, Zheng Q, Mo M, Xiong F, Hu X, Zeng Y. High Grade Trophectoderm is Associated with Monozygotic Twinning in Frozen-thawed Single Blastocyst Transfer. Arch Gynecol and Obstet. 2021 Feb. 03: [1p.]. doi: https://doi.org/10.1007/s00404-020-05928-1.
Yes Yuan S, Cheng D, Luo K, Li X, Hu L, Hu H, Wu X, Xie P, Lu C, Lu G, Lin G, Gong F, Tan YQ. Reproductive Risks and Preimplantation Genetic Testing Intervention for X-autosome Translocation Carriers. Reproductive BioMedicine. 2021 March 17: [1p.]. doi:https://doi.org/10.1016/j.rbmo.2021.03.010.
Yes Zhao M, Li H, Li R, Li Y, Luo X, Li TC, Lee TL, Wang WJ, Chan DYL. Automated and Precise Recognition of Human Zygote Cytoplasm: A Robust Image-segmentation System Based on a Convolutional Neural Network. Biomedical Signal Processing and Control. 2021 May; 67: 1-9. doi:https://doi.org/10.1016/j.bspc.2021.102551. Open Access Article

Available? Reference
No Bartolucci AF, Uliasz T, Peluso JJ. MicroRNA-21 as a Regulator of Human Cumulus Cell Viability and its Potential Influence on the Developmental Potential of the Oocyte. Biology Reproduction. 2020 Apr 25: [1p.]. doi:https://doi.org/10.1093/biolre/ioaa058.
No Deng J, Zhao Q, Cinnioglu C, Kayali R, Lathi RB, Behr B. The Impact of Culture Conditions on Blastocyst Formation and Aneuploidy Rates: a Comparison Between Single-Step and Sequential Media in a Large Academic Practice. J Assist Reprod and Genet. 2020 January; 37(1): 161-169. doi: https://doi.org/10.1007/s10815-019-01621-8.
Yes Du S, Lin YH, Sun Y, Chen QF, Huang ZQ, Su JQ, Zheng BH. Validation of Next-Generation Sequencing and Array Comparative Genomic Hybridization for Diagnosis and Screening of Reciprocal and Robertsonian Translocations in Human Blastocysts. Molecular Genetics. 2020 June 25: 1-17. doi:10.21203/rs.3.rs-37764/v1. Open Access Article
Yes Ebrahimian N, Montazeri F, Sadeghi MR, Kalantar SM, Gilany K, Ali Khalili M. Reanalysis of Discarded Blastocysts for Autosomal Aneuploidy After Sex Selection in Cleavage-stage Embryos. Clin Exp Reprod Med. 2020 June 11; 47(4): 293-299. doi: https://doi.org/10.5653/cerm.2019.03426. Open Access Article
No Guo N, Deng T, Jiang H, Gong Y, Yin L, Ren X, Jin L, Li Y. Association Between Blastocyst Morphology and Live Birth Rate Following Frozen–thawed Single Blastocyst Transfer: Results From a 5‐year Retrospective Analysis of 2593 Cryopreserved Blastocysts. Obstetrics and Gynaecology Research. 2020 Sept. 13: [1p]. doi:https://doi.org/10.1111/jog.14423.
Yes Harun MD. Medical Image Segmentation for Embryo Image Analysis [master's thesis]. [Manoa, HI]:University of Hawaii; 2020. 56p. Open Access Article
No Hirata K, Goto S, Izumi Y, Taguchi M, Hayashi A, Fujioka M, Ishiko A, Nakanishi K, Kimura F, Murakami T. Chromosome Analysis of Blastocysts Derived from Single Pronuclear Zygotes by Array CGH and Clinical Outcomes by the Transfer of Single Pronuclear Zygotes. Assisted Reproduction Technologies. 2020 May 15: [1p.]. doi: https://doi.org/10.1007/s10815-020-01800-y.
No Hoyos LR, Cheng CY, Brennan K, Hubert G, Wang B, Buyalos RP, Quinn M, Shamonki M. Euploid Rates Among Oocyte Donors: Is There an Optimal Age for Donation? Jrnl of Assist Reprod and Genet. 2020 Jan 18: 1-6. doi: https://doi.org/10.1007/s10815-020-01694-w.
 No Irani M, Canon C, Robles A, Maddy B, Gunnala V, Qin X, Zhang C, Xu K, Rosenwaks Z. No Effect of Ovarian Stimulation and Oocyte Yield on Euploidy and Live Birth Rates: an Analysis of 12,298 Trophectoderm Biopsies. Human Reproduction. 2020 April 29: [1p.]. doi: https://doi.org/10.1093/humrep/deaa028.
No Jalalie L, Rezaee MA, Rezaie MJ, Jalili A, Raoofi A, Rustamzade A. Human Umbilical Cord Mesenchymal Stem Cells Improve Morphometric and Histopathologic Changes of Cyclophosphamide-injured Ovarian Follicles in Mouse Model of Premature Ovarian Failure. Acta Histochemica. 2021 Jan; 123(1): [1p.]. doi: https://doi.org/10.1016/j.acthis.2020.151658
No Jiang S, Peng X, Gong F, Huang C, Peng Y, Long X, Lin G, Zhu W. The Role of Total Chromosomal Disomy in Human Spermatozoa as a Predictor of the Outcome of Pre-Implantation Genetic Screening. Fertility and Sterility. 2020 June; 113 (6): 1196-1204. doi:https://doi.org/10.1016/j.fertnstert.2020.02.004.
No Kim HJ, Park JK, Eum JH, Song H, Lee WS, Lyu SW. Embryo Selection Based on Morphological Parameters in a Single Vitrified-Warmed Blastocyst Transfer Cycle. Reprod. Sci. 2020 Oct. 13: [1p]. doi:https://doi.org/10.1007/s43032-020-00349-6.
No Kuliev A, Rechitsky S, Simpson JL. Major Components of Preimplantation Genetic Testing. Practice Preimplantation Genetic Testing. 2020 May 30: 13-30. doi: https://doi.org/10.1007/978-3-030-43157-0_2.
Yes Kuznyetsov V, Madjunkova S, Abramov R, Antes R, Ibarrientos Z, Motamedi G, Zaman A, Kuznyetsova I, Librach CL. Minimally Invasive Cell-Free Human Embryo Aneuploidy Testing (miPGT-A) Utilizing Combined Spent Embryo Culture Medium and Blastocoel Fluid –Towards Development of a Clinical Assay. Scientific Reports. 2020 April 29; 10(1): 1-9. doi:10.1038/s41598-020-64335-3. Open Access Article
No Liu C, Su K, Shang W, Ji H, Yuan C, Cao M, Li C, Zhou X. Higher Implantation and Live Birth Rates with Laser Zona Pellucida Breaching Than Thinning in Single Frozen-thawed Blastocyst Transfer. 2020 Jan. 03: [1p.]. doi: https://doi.org/10.1007/s10103-019-02946-7.
No Makhijani R, Bartels CB, Godiwala P, Bartolucci A, DiLuigi A, Nulsen J, Grow D, Benadiva C, Engmann L. Impact of Trophectoderm Biopsy on Obstetric and Perinatal Outcomes Following Frozen–thawed Embryo Transfer Cycles. Human Reproduction. 2020 Dec. 12; deaa316 : [1p.]. doi:https://doi.org/10.1093/humrep/deaa316.
No McDaniel KE, Awadalla MS, McGinnis LK, Ahmady A. Transfer the Best and Biopsy the Rest? Blastocyst Euploidy Rates Differ by Morphology and Day of Biopsy. Archives of Gynecology and Obstetrics. 2020 Aug. 17: [1p]. doi: https://doi.org/10.1007/s00404-020-05746-5.
No Niu X, Lao Y, Sun Y, Wang W. Next-Generation Sequencing Revealed that High Proportion of Human Embryos Resulted from Donor Eggs Are Segmental Chromosome Abnormal [Online First]. IntechOpen. 2020 Dec. 30: 1-13. doi:10.5772/intechopen.95457.
Yes Niu X, Long J, Gong F, Wang W. Does ICSI for in vitro fertilization cause more aneuploid embryos? Molecular Cytogenetics. 2020 July 01; 13(27): 1-7. doi: https://doi.org/10.1016/j.rbmo.2013.11.018. Open Access Article
Yes Niu X, Ruan Q, Witz CA, Wang W. Comparison of Human Oocyte Activation Between Round-Headed Sperm Injection Followed by Calcium Ionophore Treatment and Normal Sperm Injection in a Patient With Globozoospermia. Front. Endocrinol. 2020 April 07; 11 (183): [1p.]. doi: https://doi.org/10.3389/fendo.2020.00183. Open Access Article
No Ramos N, Aycock H, Johnson D, Haimowitz Z, Akopians A, Barritt J. Laser Assisted Hatching of Human Embryos at Fertilization Check, on Day 1 of Culture, Allows for Continuous Uninterrupted Time-Lapse Incubation of 5+ Days, While Producing Hatching Blastocysts as Expected. Reproductive BioMedicine. 2020 Oct; 41(1): e4-e5. doi:https://doi.org/10.1016/j.rbmo.2020.08.025.
Yes Sachdev NM, McCulloh DH, Kramer Y, Keefe D, Grifo JA. The Reproducibility of Trophectoderm Biopsies in Euploid, Aneuploid, and Mosaic Embryos Using Independently Verified Next-Generation Sequencing (NGS): a pilot study. Jrnl of Assist Reprod Genet (2020). 2020 Feb. 13: [1p.]. doi: https://doi.org/10.1007/s10815-020-01720-x. Open Access Article
Yes Schaeffer E, Porchia LM, Neumann A, Luna A, Rojas T, López‑Bayghen E. Embryos Derived from Donor or Patient Oocytes are Not Different for In Vitro Fertilization Outcomes When PGT Allows Euploid Embryo Selection: a Retrospective Study. Clinical and Translational Medicine. 2020 Feb. 07; 9(14): 1-10. doi: https://doi.org/10.1186/s40169-020-0266-1. Open Access Article
Yes  Takeuchi K. Pre‐implantation Genetic Testing: Past, Present, Future. Reproductive Medicine and Biology. 2020 Oct. 13; 00: 1-14. doi: https://doi.org/10.1002/rmb2.12352. Open Access Article
No Tan J, Jing C, Zhang L, Lo J, Kan A, Nakhuda G. GnRH Triggering May Improve Euploidy and Live Birth Rate in Hyper-Responders: a Retrospective Cohort Study. Journal of Assisted Reproduction and Genetic. 2020 June 13: [1p.]. doi:https://doi.org/10.1007/s10815-020-01842-2.
No Tang M, Popovic M, Stamatiadis P, Van der Jeught M, Coster RV, Deforce D, De Sutter P, Coucke P, Menten B, Stoop D, Boel A, Heindryckx B. Germline Nuclear Transfer in Mice May Rescue Poor Embryo Development Associated with Advanced Maternal Age and Early Embryo Arrest. Hum Reprod. 2020 July 2: [1p.]. doi: 10.1093/humrep/deaa112.
Yes  Tiewsiri K, Manipalviratn S, Sutheesophon W, Vanichsetakul P, Thaijaroen P, Ketcharoon P, Bradley CK, McArthur SJ, Krutsawad W, Marshall JTA, Papadopoulos KI. The First Asian, Single-Center Experience of Blastocyst Preimplantation Genetic Diagnosis with HLA Matching in Thailand for the Prevention of Thalassemia and Subsequent Curative Hematopoietic Stem Cell Transplantation of Twelve Affected Siblings. Clinical Study. 2020 June 26: 1-10. doi: https://doi.org/10.1155/2020/5292090. Open Access Article
No Yadav G, Yang L, Kaskar K, Cochran R, Selvanesan B, Gibbons W. Poor Blastocyst Formation from Good Quality Day Three Embryos is Associated with Asthenospermia. Reproductive BioMedicine Online. 2020 Oct; 41(1): e5-e6. doi:https://doi.org/10.1016/j.rbmo.2020.08.026.
 No Zhan Q, Sierra ET, Malmsten J, Ye Z, Rosenwalks Z, Zaninovic N. Blastocyst Score, a Blastocyst Quality Ranking Tool, is a Predictor of Blastocyst Ploidy and Implantation Potential. F & S Reports. 2020 Sept; 1(2): 133-141. doi:https://doi.org/10.1016/ j.xfre.2020.05.004.

Available? Reference
No Anderson RE, Whitney JB, Schiewe MC. Clinical Benefits of Preimplantation Genetic Testing for Aneuploidy (PGT-A) for all In Vitro Fertilization Treatment Cycles. European Journal of Medical Genetics. 2019 July 27: [1p.]. doi:https://doi.org/10.1016/j.ejmg.2019.103731.
No He H, Jing S, Lu CF, Tan YQ, Luo KL, Zhang SP, Gong F, Lu GX, Lin G. Neonatal Outcomes of Live Births After Blastocyst Biopsy in Preimplantation Genetic Testing Cycles: A Follow-Up Of 1,721 Children. Fert and Steril. 2019 May 2: 1-6. doi: https://doi.org/10.1016 /j.fertnstert.2019.03.006.
No Hernandez-Nieto C, Lee JA, Slifkin R, Sandler B, Copperman AB, Flisser E. What is the Reproductive Potential of Day 7 Euploid Embryos? Human Reproduction. 2019 Sept; 34(9): 1697–1706. doi: https://doi.org/10.1093/humrep/dez129.
No Huang L, Bogale B, Tang Y, Lu S, Xie XS, Racowsky C. Noninvasive Preimplantation Genetic Testing for Aneuploidy in Spent Medium May Be More Reliable than Trophectoderm Biopsy. PNAS. 2019 June 24: [1p.]. doi: https://doi.org/10.1073/pnas.1907472116.
No Johnson D, Haimowitz Z, Arifova M, Akopians A, Welch C, Barritt J. Repeated High Intensity Laser Biopsy Pulses Do Not Alter Genetic Testing Results Nor Increases Mosaicism Following Human Embryo Blastocyst Biopsy of Trophectoderm Cells.Reprod Biomed Online. 2019 Sept; 39(2): e4-e5. doi: https://doi.org/10.1016/j.rbmo.2019.07.013.
Yes Kim MK, Park JK, Jeon Y, Choe SA, Lee HJ, Kim J, Chang EM, Kim JW, Lyu SW, Kim JY, Kwak IP, Lee WS, Yoon TK. Correlation between Morphologic Grading and Euploidy Rates of Blastocysts, and Clinical Outcomes in In Vitro Fertilization Preimplantation Genetic Screening. J Korean Med Sci. 2019 Jan 28; 34(4): 1-11. doi:https://doi.org/10.3346 /jkms. 2019.34.e27. Open Access Article
Yes Kim MK, Park JK, Jeon Y, Seok SH, Chang EM, Lee WS. Effects of Paternal Age on Human Embryo Development in In Vitro Fertilization with Preimplantation Genetic Screening. Clin Exp Reprod Med. 2019 Jan 31; 46(1):22-29. doi:https://doi.org/10.5653/cerm.2019.46.1.22. Open Access Article
No Lu X, Liu Y, Cao X, Liu SY, Dong X. Laser-assisted hatching and Clinical Outcomes in Frozen-thawed Cleavage-embryo Transfers of Patients with Previous Repeated Failure. Lasers in Medical Science. 2019 Jan 09: [1p.]. doi:https://doi.org/10.1007/s10103-018-02702-3
No Luo K, Lan Y, Xie P, Gong F, Xiong B, Tan Y, Zhou S, Yang Z, Lin G, Hu L. Next-Generation Sequencing Analysis of Embryos from Mosaic Patients Undergoing In Vitro Fertilization and Preimplantation Genetic Testing. Fertility and Sterility. 2019 May 24: 1-6. doi:https://doi.org/10.1016/j.fertnstert.2019.03.035.
No Otsuki J, Iwasaki T, Enatsu N, Katada Y, Furuhashi K, Shiotani M. Noninvasive Embryo Selection: Kinetic Analysis of Female and Male Pronuclear Development to Predict Embryo Quality and Potential to Produce Live Birth. Fertility and Sterility. 2019 Nov; 112(5): 874-881. doi:https://doi.org/10.1016/j.fertnstert.2019.07.015.
No Ozgur K, Berkkanoglu M, Bulut H, Yoruk GDA, Candurmaz NN, Coetzee K. Single Best Euploid Versus Single Best Unknown-Ploidy Blastocyst Frozen Embryo Transfers: A Randomized Controlled Trial. J Assist Reprod and Genet. 2019 Jan 07: [1p.]. doi:https://doi.org/10.1007/s10815-018-01399-1.
No Ozgur K, Bulut H, Berkkanoglu M, Donmez L, Coetzee K. Prediction of Live Birth and Cumulative Live Birth Rates in Freeze-all-IVF Treatment of a General Population. J Assist Reprod Genet (2019). 2019 Feb 21: 1-12. doi:https://doi.org/10.1007/s10815-019-01422-z.
No Ozgur K, Bulut H, Berkkanoglu M, Humaidan P, Coetzee K. Large for Gestational Age is Male Gender Dependent in Artificial Frozen Embryo Transfers Cycles – a Cohort Study of 1295 Singleton Live Births. Reprod BioMed. 2019 Oct 24: [1p.]. doi:https://doi.org/10.1016/j.rbmo.2019.10.010.
No Popovic M, Dhaenens L, Taelman J, Dheedene A, Bialecka M, De Sutter P, Chuva de Sousa Lopes SM, Menten B, Heindryckx B. Extended In Vitro Culture of Human Embryos Demonstrates the Complex Nature of Diagnosing Chromosomal Mosaicism from a Single Trophectoderm Biopsy. Human Reproduction. 2019 March 6: [1p.]. doi:https://doi.org/10.1093/humrep/dez012.
Yes Ramos N, Johnson D, Eisman L, Haimowitz Z, Surrey M, Danzer H, Barritt J. The Survival, Biopsy, Ploidy and Pregnancy Rates of Previously Vitrified Blastocysts Subjected to Warming/Biopsy/Revitrification for PGT-A Analysis. Fertil Steril. 2019 April; 111(4):36-37. Open Access Article
No Sagi I, De Pinho JC, Zuccaro MV, Atzmon C, Golan-Lev T, Yanuka O, Prosser R, Sadowy A, Perez G, Cabral T, Glaser B, Tsang SH, Goland R, Sauer MV, Lobo R, Benvenisty N, Egli D. Distinct Imprinting Signatures and Biased Differentiation of Human Androgenetic and Parthenogenetic Embryonic Stem Cells. CellPress. 2019 Sept 5; 25(3): 419-432. doi: https://doi.org/10.1016/j.stem.2019.06.013.
No Singh S, Hobeika E, Knochenhauer ES, Traub ML. Pregnancy Rates After Pre-Implantation Genetic Screening For Aneuploidy Are Only Superior When Trophectoderm Biopsy Is Performed On Hatching Embryos. Jrnl Assist Reprod Genet. 2019 Jan 15: 1-8. doi:https://doi.org/10.1007/s10815-019-01400-5
No Stein D, Ukogu C, Ganza A, Gounko D, Lee J, Bar-Chama N, Copperman AB. Paternal Contribution to Embryonic Competence. Cent European J Urol. 2019 Sept 2; 72(3): 296-301. doi: 10.5173/ceju.2019.1900.
No Taylor TH, Stankewicz T, Katz SL, Patrick JL, Johnson L, Griffin DK. Preliminary Assessment of Aneuploidy Rates Between the Polar, Mid and Mural Trophectoderm. Cambridge University Press. 2019 Dec. 18: [1p.]. doi:https://doi.org/10.1017/S096719 9419000637.
Yes Tšuiko O, Zhigalina DI, Jatsenko T, Skryabin NA, Kanbekova OR, Artyukhova VG, Svetlakov AV, Teearu K, Trošin A, Salumets A, Kurg A, Lebedev IN. The Karyotype of the Blastocoel Fluid Demonstrates Low Concordance with Both Trophectoderm and Inner Cell Mass [Epub ahead of print]. University of Tartu Estonia. 2019 Nov: 1-20. Open Access Article
Yes Tsuiko O. Unravelling Chromosomal Instability in Mammalian Preimplantation Embryos Using Single-cell Genomics [dissertation].[Estonia]: Universitatis Tartuensis; 2018 Aug 22. 168p. Open Access Article
No Wilkinson S, Cunningham A, Murray R, Scotchie J, Jones A. Thrice Vitrified and Warmed, Twice Biopsied Embryo Originating from a Cohort of unfertilized eggs resulted in live birth: A case report. RBMO. 2019 Sept 25; 39 (2): e5-e6. doi:https://doi.org/10.1016/j.rbmo.2019 .07.014.
No Xie PY, Hu L, Tan Y, Gong F, Zhang SP, Xiong B, Peng Y, Lu GX, Lin G. Retrospective analysis of meiotic segregation pattern and interchromosomal effects in blastocysts from inversion preimplantation genetic testing cycles. Fert and Steril. 2019 May 15: 1-6. doi:https://doi.org/10.1016/j.fertnstert.2019.03.041.
No Xiong F, Li G, Sun Q, Chen P, Wang Z, Wan C, Yao Z, Zhong H, Zeng Y. Obstetric and Perinatal Outcomes of Pregnancies According to Initial Maternal Serum HCG Concentrations After Vitrified–Warmed Single Blastocyst Transfer. Reproductive BioMedicine Online. 2019 Jan 5: [1p.]. doi:https://doi.org/10.1016/j.rbmo.2018.12.040.
No Xiong F, Li G, Sun Q, Wang S, Wan C, Chen P, Yao Z, Zhong H, Zeng Y. Clinical Outcomes After Transfer of Blastocysts Derived From Frozen–thawed Cleavage Embryos: a Retrospective Propensity-matched Cohort Study. Gynecol and Obstet. 2019 July 4: 1-11. doi:https://doi.org/10.1007/s00404-019-05236-3.
No Yumoto K, Shimura T, Sugishima M, Mio Y. A Novel Zona-free Culture System for Severe Cytoplasmic Fragmentation Cases: a Pilot Study using 3PN Embryos and Time-lapse Cinematography. Fertility and Sterility. 2019 Oct 15; 112(3): 41. doi: https://doi.org/10.1016/j.fertnstert.2019.07.444.
No Zhang Z, Dai C, Wang X, Ru C, Abdalla K, Jahangiri S, Librach C, Jarvi K, Sun Y. Automated Laser Ablation of Motile Sperm for Immobilization. IEEE Robotics and Automation Letters. 2019 Jan 1; 4(2):323-329. doi:10.1109/LRA.2018.2890445.

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No Ashiru OA, Ogbeche RO, Oladimeji MO, Iloabachie EC, Umana AE, Osumah JG. Blastocyst and Cleavage Stage Embryo Biopsy for Preimplantation Genetic Testing of the Sickle Cell Gene in Carrier Couples: the Experience of an IVF Clinic in a Developing Country a Retrospective Study. Global Reproductive Health. 2018 July 18: [1p.]. doi:10.1097/GRH.0000000000000017.
No Coughtrie DJ, Giereth R, Kats D, Werner HJ, Kohn A. Embedded Multireference Coupled Cluster Theory. J. Chem. Theory Comput. 2018 Jan 18: [1p.]. doi: 10.1021/acs.jctc.7b01144.
No Davidson LN, Liu Y, Griffiths T, Jones C, Coward K. Laser technology in the assisted reproductive technology laboratory: a narrative review. Reproductive Biomedicine Online. 2018 Dec 20: [1p.]. doi:https://doi.org/10.1016/j.rbmo.2018.12.011.
Yes Desai N, Goldberg JM, Austin C, Falcone T. Are Cleavage Anomalies, Multinucleation, or Specific Cell Cycle Kinetics Observed With Time-Lapse Imaging Predictive of Embryo Developmental Capacity or Ploidy? Fertility and Sterility. 2018 Feb 13: 1-10. doi: https://doi.org/10.1016/j.fertnstert.2017.12.025.
No Frank LA, Rose RD, Anastasi MR, Tan TCY, Barry MF, Thompson JG, Brown HM. Artificial Blastocyst Collapse Prior to Vitrification Significantly Improves Na+/K+-ATPase-Dependent Post-Warming Blastocoel Re-Expansion Kinetics Without Inducing Endoplasmic Reticulum Stress Gene Expression in the Mouse. Reproduction, Fertility and Development. 2018 Aug 13: [1p.]. doi: https://doi.org/10.1071/RD17500.
Yes Gordon C, Whitney JB, Hatch I, Nugent NL, Zozula S, Anderson RE, Schiewe MC. Patients of Advanced Maternal Age Should Only Transfer a Single Euploid Blastocyst. Clin Obstet Gynecol Reprod Med. 2018 March 16; 4(2):1-4. doi: 10.15761/COGRM.1000211. Open Access Article
No Guzman L, Nunez D, Lopez R, Inoue N, Portella J, Vizcarra F, Noriega-Portella L, Noriega-Hoces L, Munne S. The Number of Biopsied Trophectoderm Cells May Affect Pregnancy Outcomes. Journal of Assisted Reproduction and Genetics. 2018 Oct 17: 1-7. doi: https://doi.org/10.1007/s10815-018-1331-1
Yes Hao Y, Chen D, Zhang Z, Zhou P, Cao Y, Wei Z, Xu X, Chen B, Zou W, Lv M, Ji D, He X. Successful Preimplantation Genetic Diagnosis By Targeted Next-Generation Sequencing on an Ion Torrent Personal Genome Machine Platform. Oncology Letters. 2018 Jan 26: 1-7. doi: 10.3892/ol.2018.7876. Open Access Article
Yes Ho JR, Arrach N, Rhodes-Long K, Ahmady A, Ingles S, Chung K, Bendikson KA, Paulson RJ, McGinnis LK. Pushing the limits of detection: investigation of cell-free DNA for aneuploidy screening in embryos. Fertility and Sterility. 2018 June 28: [1p.]. doi:https://doi.org/10.1016/j.fertnstert.2018.03.036.
No Ho JR, Arrach N, Rhodes-Long K, Salem W, McGinnis LK, Chung K, Bendikson KA, Paulson RJ, Ahmady A. Blastulation Timing is Associated with Differential Mitochondrial Content in Euploid Embryos. Embryo Biology. 2018 Jan 20: [1p.]. doi: https://doi.org/10.1007/s10815-018-1113-9.
Yes Hu L, Wei Y, Luo K, Xie P, Gong F, Xiong B, Tan Y, Lu G, Lin G. Clinical Outcomes in Carriers of Complex Chromosomal Rearrangements: a Retrospective Analysis of Comprehensive Chromosome Screening Results in Seven Cases. Fertility and Sterility. 2018 Feb 7: 1-7. doi: https://doi.org/10.1016/j.fertnstert.2017.11.021.
Yes Nakhuda G, Jing C, Butler R, Guimond C, Hitkari J, Taylor E, Tallon N, Yuzpe A. Frequencies of chromosome-specific mosaicisms in trophoectoderm biopsies detected by next-generation sequencing. Fertility and Sterility. 2018 May 17; 109(5):857-865. doi: https://doi.org/10.1016/j.fertnstert.2018.01.011.
No Nazem TG, Sekhon L, Lee JA, Overbey J, Pan S, Duke M, Briton-Jones C, Whitehouse M, Copperman AB, Stein DE. The correlation between morphology and implantation of euploid human blastocysts. Reproductive BioMedicine. 2018 Dec 07: [1p.]. doi:https://doi.org/10.1016/j.rbmo.2018.10.007.
Yes Ocampo A, Pedraza J, Ortiz G, Hernandez-Perez E, Porchia L, Lopez-Bayghen E. Assessment of Prostaglandin-Endoperoxide Synthase 2 and Versican Gene Expression Profile from the Cumulus Cells: Association with Better In Vitro Fertilization Outcomes. Journal of Ovarian Research. 2018 Sept 21; 11(84): 1-10. doi:https://doi.org/10.1186/s13048-018-0456-2. Open Access Article
No Priner S, Altarescu G, Schonberger O, Holzer H, Rubinstein E, Dekel N, Peretz A, Eldar-Geva T. The effect of repeated biopsy on pre-implantation genetic testing for monogenic diseases (PGT-M) treatment outcome. Journal of Assisted Reproduction and Genetics. 2018 Nov 6: 1-6. doi: https://doi.org/10.1007/s10815-018-1359-2.
No Popovic M, Dheedene A, Christodoulou C, Taelman J, Dhaenens L, Van Nieuwerburgh F, Deforce D, Van den Abbeel E, De Sutter P, Menten B, Heindryckx B. Chromosomal mosaicism in human blastocysts: the ultimate challenge of preimplantation genetic testing? Human Reproduction. 2018 May 23; dey106:[1p.]. doi: https://doi.org/10.1093/humrep/dey106.
No Rocafort E, Enciso M, Leza A, Sarasa J, Aizpurua J. Euploid Embryos Selected by an Automated Time-lapse System have Superior SET Outcomes than Selected Solely by Conventional Morphology Assessment. J Assist Reprod Genet. 2018 July 20: [1p.]. doi: https://doi.org/10.1007/s10815-018-1265-7.
No Sevilla A, Forero E, Zimmer M, Martinez H, Reggio K, Paull D, Egli D, Noggle S. Derivation and characterization of the NIH registry human stem cell line NYSCF100 line under defined feeder-free conditions. 2018 May; 29: 99-102. Doi: https://doi.org/10.1016/j.scr.2018.03.017.
No Tannus S, Cohen Y, Henderson S, Son WY, Tulandi T. The Effect of Assisted Hatching on Live Birth Rate Following Fresh Embryo Transfer in Advanced Maternal Age. Reproductive Sciences. 2018 Sept 13: [1p.]. doi: https://doi.org/10.1177/19337191187991 92.
No Tejwani V, Andersen MR, Nam JH, Sharfstein ST. Glycoengineering in CHO Cells: Advances in Systems Biology. Biotechnology Journal. 2018 Jan 5: [1p.]. doi:10.1002/biot.201700234.
Yes Tsuiko O, Zhigalina DI, Jatsenko T, Skryabin NA, Kanbekova OR, Artyukhova VG, Svetlakov AV, Teearu K, Trosin A, Salumets A, Kurg A, Lebedev IN. Karyotype of the blastocoel fluid demonstrates low concordance with both trophectoderm and inner cell mass. Fertility and Sterility. 2018 June; 109 (6): 1127-1134. doi:https://doi.org/10.1016/ j.fertnstert.2018 .02.008.
No Warrier S, Taelman J, Tilleman L, Van der Jeught M, Duggal G, Lierman S, Popovic M, Soom AV, Peelman L, Nieuwerburgh FV, Deforce D, Chuva de Sousa Lopes SM, De Sutter P, Heindryckx B. Transcriptional Landscape Changes During Human Embryonic Stem Cell Derivation. 2018 Sept 17: [1p.]. doi:https://doi.org/10.1093/molehr/gay039
Yes Xie PY, Tang Y, Hu L, Ouyang Q, Gu YF, Gong F, Leng LZ, Zhang SP, Xiong B, Lu GX, Lin G. Identification of Biparental and Diploid Blastocysts from Monopronuclear Zygotes with the Use of a Single-Nucleotide Polymorphism Array. Fertility and Sterility. 2018 Aug; 110(3): 545-554. doi: https://doi.org/10.1016/j.fertnstert.2018.04.034.
No Yu C, Zhang R, Li J, Zhou A. A Predictive Model for High-Quality Blastocyst Based on Blastomere Number, Fragmentation, and Symmetry. J Assist Reprod Genet. 2018 March 3: 1-8. doi: https://doi.org/10.1007/s10815-018-1132-6.
No Zeyad A, Al-Abdulkareem B, Hammadeh ME. The Relationship Between Preimplantation Morphokinetics of Human Embryos and Sex Chromosome Pattern. Reproductive Biology. 2018 Oct 19: [1p.]. doi: https://doi.org/10.1016/j.repbio.2018.10.002.
No Zhao H, Li T, Zhao Y, Tan T, Liu C, Huang N, Li C, Fan Y, Yu Y, Li R, Qiao J. Single-Cell Transcriptomics of Human Oocytes: Environment-Driven Metabolic Competition and Compensatory Mechanisms During Oocyte Maturation. ARS. 2018 Feb 27: [1p.]. doi: https://doi.org/10.1089/ars.2017.7151.
No Zhou S, Cheng D, Ouyang Q, Xie P, Lu C, Gong F, Hu L, Tan Y, Lu G, Lin G. Prevalence and Authenticity of De-Novo Segmental Aneuploidy (>16 Mb) in Human Blastocysts as Detected by Next-Generation Sequencing. Reproductive BioMedicine Online. 2018 Aug 29: [1p.]. doi:https://doi.org/10.1016/j.rbmo.2018.08.006.

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No Barash OO, Ivani KA, Willman SP, Rosenbluth EM, Wachs DS, Hinckley MD, Reid SP, Weckstein LN. Association between growth dynamics, morphological parameters, the chromosomal status of the blastocysts, and clinical outcomes in IVF PGS cycles with single embryo transfer. 2017 May 30: 1-10. doi: 10.1007/s10815-017-0944-0.
No Bradley CK, Livingstone M, Traversa MV, McArthur SJ. Impact of Multiple Blastocyst Biopsy and Vitrification-Warming procedures on pregnancy outcomes. Fertility and Sterility. 2017 Oct 31: [1p.]. doi: http://dx.doi.org/10.1016/j.fertnstert.2017.09.013.
No Bradley CK, Traversa M, Hobson N, Gee AJ, McArthur SJ. Clinical Use Of Monopronucleated Zygotes Following Blastocyst Culture And Preimplantation Genetic Screening, Including Verification Of Biparental Chromosome Inheritance. Reproductive BioMedicine. 2017 March 27: [1p.]. doi: http://dx.doi.org/10.1016/j.rbmo.2017.03.013.
No De Vos A. Embryo Biopsy by Laser on Day 5 in the IVF Laboratory. Principles of IVF Laboratory Practice: Optimizing Performance and Outcomes. New York Cambridge University Press; 2017. 245p.
No Dheedene A. Innovations in Cytogenomic Technologies for Prenatal Diagnosis. Ghent University Academic Bibliography. 2017 July 12: 187. doi: http://hdl.handle.net/1854/LU-8526636.
No Dieamant F, Petersen CG, Mauri Al, Conmar V, Matilla M, Vagnini LD, Renzi A, Petersen B, Ricci J, Oliveira JBA, Baruffi RLR, Franco JG. P-01. Single step versus sequential culture medium: what is the best choice to improve ongoing pregnancy rate? A systematic review and meta-analysis. JBRA Assist Reprod. 2017 Apr-Jun; 21(2): 142-160. doi: https://doi.org/10.3168/jds.2016-12531
No Feldman B, Aizer A, Brengauz M, Dotan K, Levron J, Schiff E, Orvieto R. Pre-implantation genetic diagnosis—should we use ICSI for all? J Assist Reprod Genet (2017). 2017 June 13: 1-5. doi:10.1007/s10815-017-0966-7.
No Go KJ, Pool TB. Troubleshooting in the IVF Laboratory. Principles of IVF Laboratory Practice: Optimizing Performance and Outcomes. New York Cambridge University Press; 2017. 306p.
No Hernandez-Nieto C, Lee J, Nazem T, Gounko D, Copperman A, Sandler B. Embryo Aneuploidy is Not Impacted by Selective Serotonin Reuptake Inhibitor Exposure. 2017 Dec; 108 (6): 973-979. doi:http://dx.doi.org/10.1016/j.fertnstert.2017.08.040.
Yes Hichri R, Amor H, Khammari M, Harzallah M, El Fekih S, Saad A, Ajina M, Ben Ali H. Apoptotic sperm biomarkers and the correlation between conventional sperm parameters and clinical characteristics. Andrologia. 2017 May 10; 2017 (e12813): 1-9. doi: https://doi.org/10.1111/and.12813. Open Access Article
No Lewis EI, Farhadifar R, Farland LV, Needleman DJ, Missmer SA, Racowsky C. Use of imaging software for assessment of the associations among zona pellucida thickness variation, assisted hatching, and implantation of day 3 embryos. J Assist Reprod and Genetics. 2017 July 6:1-9. doi:https://doi.org/10.1007/s10815-017-0978-3
Yes Matsubayashi H, Kitaya K, Yamaguchi K, Nishiyama R, Takaya Y, Ishikawa T. Is a high serum copper concentration a risk factor for implantation failure? BMC Research Notes 2017. 2017 Aug 10; 10: 387. doi: https://doi.org/10.1186/s13104-017-2708-4. Open Access Article
Yes Otsuki J, Iwasaki T, Tsuji Y, Katada Y, Sato H, Tsutsumi Y, Hatano K, Furuhashi K, Matsumoto Y, Kokeguchi S, Shiotani M. Potential of zygotes to produce live births can be identified by the size of the male and female pronuclei just before their membranes break down. Reproductive Medicine and Biology. 2017 April 12; 16(2): 200-205. doi:10.1002/rmb2.12032. Open Access Article
Yes Sills ES, Obregon-Tito AJ, Gao H, McWilliams TK, Gordon AT, Adams CA, Slim R. Pathogenic variant in NLRP7 (19q13.42) associated with recurrent gestational trophoblastic disease: Data from early embryo development observed during in vitro fertilization. Clin Exp Reprod Med. 2017 March 31; 44(1): 40-46. doi: https://doi.org/10.5653/cerm.2017.44.1.40. Open Access Article
No Tannus S, Turki R, Cohen Y, Son WY, Shavit T, Duhan MH. Reproductive outcomes after a single dose of gonadotropin-releasing hormone agonist compared with human chorionic gonadotropin for the induction of final oocyte maturation in hyper-responder women aged 35–40 years. Fertility and Sterility. 2017 May 10: [1p.]. doi: http://dx.doi.org/10.1016/j.fertnstert.2017.04.014.
No Taylor T. Preimplantation Genetic Screening During In Vitro Fertilization, Clinical Applications and Insight into Embryological Development. University of Kent. 2017 Dec 07: 10-279. Open Access Article
Yes Uchida H, Machida M, Miura T, Kawasaki T, Okazaki T, Sasaki K, Sakamoto S, Ohuchi N, Kasahara M, Umezawa A, Akutsu H. A xenogeneic-free system generating functional human gut organoids from pluripotent stem cells. JCI Insight. 2017 Jan 12: 1-12. doi:10.1172/jci.insight.86492. Open Access Article
Yes Zhang J, Liu H, Lu S, Chavez-Badiola A, Liu Z, Yang M, Merhi Z, Silber SJ, Munne S, Konstandinidis M, Wells D, Huang T. Live birth derived from oocyte spindle transfer to prevent mitochondrial disease. Reproductive BioMedicine Online. 2017 April 3; 34 (4): 361-368. doi: http://doi.org/10.1016/j.rbmo.2017.01.013. Open Access Article

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No Burrill D, Vernet A, Collins J, Silver PA, Way JC. Targeted erythropoietin selectively stimulates red blood cell expansion in vivo. PNAS; 113(19): 5245-5250. doi: 10.1073/pnas.1525388113.
Yes
Cedillo L, Ocampo-Barcenas A, Maldonado I, Valdez-Morales FJ, Camargo F, Lopez-Bayghen E. A simple, less invasive stripper micropipetter-based technique for day 3 embryo biopsy. Fertility Research and Practice. 2016 Nov 25; 2 (13): 1-7. doi: 10.1186/s40738-016-0027-4. Open Access Article
 Yes Elhoussieny A, El Mandooh M., Bahaa-Eldin A., Fathy H. Laser Assisted Zona Thinning Versus the Conventional Mechanical Method for Intracytoplasmic Sperm Injection in ICSI Programs. International Journal of Obstetrics and Gynaecology Research (IJOGR)2016. 3(2):221-239. Open Access Article
Yes Hu L, Cheng D, Gong F, Lu C, Tan Y, Luo K, Wu X, He W, Xie P, Feng T, Yang K, Lu G, Lin G. Reciprocal Translocation Carrier Diagnosis in Preimplantation Human Embryos. EBioMedicine. 2016 Nov 4; 14 (2016): 139-147. doi:http://dx.doi.org/10.1016/j.ebiom.2016.11.007. Open Access Article
Yes Hu Y, Trolice M. Live birth of twins derived from zona-free oocytes. Fertility and Sterility. 2016 Feb. 6; 105 (2): 247-544. doi: http://dx.doi.org/10.1016/j.fertnstert.2016.01.023.
Yes Jing S, Luo K, He H, Lu C, Zhang S, Tan Y, Gong F, Lu G, Lin G. Obstetric and neonatal outcomes in blastocyst-stage biopsy with frozen embryo transfer and cleavage-stage biopsy with fresh embryo transfer after preimplantation genetic diagnosis/screening. Fertility and Sterility. 2016 March 19: 1-12. doi:http://dx.doi.org/10.1016/j.fertnstert.2016.03.010.
Yes Kang HJ, Melnick AP, Stewart JD, Xu K, Rosenwaks Z. Preimplantation genetic screening:who benefits? Fertility and Sterility. 2016 April 30: 1-16. doi:10.1016/j.fertnstert.2016.04.027.
Yes Lin D, Ran J, Chen C, Luo Z, Quan S, Ye B, Yu A, Kang Y, Lin Y. Frozen two day 3 embryos and subsequently produced blastocysts by vitrification: advantages for IVF/ICSI patients at high risk of ovarian hyperstimulation syndrome. IJCEM; 9(3): 6986-6999. Open Access Article
Yes Liu M, Su Y, Wang WH. Assessment of clinical application of preimplantation genetic screening on cryopreserved human blastocysts. Reproductive Bio and Endocrinology. 2016 April 8; 14(16):1-7. doi: 10.1186/s12958-016-0155-z. Open Access Article
Yes Otsuki J, Iwasaki T, Katada Y, Sato H, Furuhashi K, Tsuji Y, Matsumoto Y, Shiotani. Grade and looseness of the inner cell mass may lead to the development of monochorionic diamniotic twins. Fertility and Sterility. 2016 June 2: 1-5. doi: http://dx.doi.org/10.1016/j.fertnstert.2016.05.007.
Yes Ou J, Wang W, Feng T, Liao L, Meng Q, Zou Q, Ding J, Zheng A, Duan C, Li P, Liu Q, Lin C, Li H. Identification of small segmental translocations in patients with repeated implantation failure and recurrent miscarriage using next generation sequencing after in vitro fertilization/intracytoplasmic sperm injection. Mol Cytogenet. 2015 Dec 30;8:105. doi: 10.1186/s13039-015-0207-7. eCollection 2015. PubMed PMID: 26719770; PubMed Central PMCID: PMC4696251. Open Access Article
Yes Richter KS, Ginsburg DK, Shipley SK, Lim J, Tucker MJ, Graham JR, Levy MJ. Factors associated with birth outcomes from cryopreserved blastocysts: experience from 4,597 autologous transfers of 7,597 cryopreserved blastocysts. Fertility and Sterility. 2016 May 9:1-8. doi: 10.1016/j.fertnstert.2016.04.022.
No Rodriguez-Purata J, Gingold J, Lee J, Whitehouse M, Slifkin R, Briton-Jones C, Copperman A, Sandler B. Hatching status before embryo transfer is not correlated with implantation rate in chromosomally screened blastocysts. Hum. Reprod. 2016 Oct 21: [1p.]. doi: 10.1093/humrep/dew205.
 No Rodriguez-Purata J, Lee J, Whitehouse M, Duke M, Grunfeld L, Sandler B, Copperman A, Mukherjee T. Reproductive outcome is optimized by genomic embryo screening, vitrification, and subsequent transfer into a prepared synchronous endometrium. J Assist Reprod Genet. 2016 Jan 14. [Epub ahead of print] PubMed PMID: 26768140
Yes Shi W, Hongwei T, Zhang W, Li N, Li M, Shi J. A Prospective Randomized Controlled Study of Laser-Assisted Hatching on the Outcome of First Fresh IVF-ET Cycle in Advanced Age Women. Reproductive Sciences. 2016 April 12; 23(10): 1397-1401. doi: https://doi.org/10.1177/1933719116641764.
No Shu Y, Prokai D, Berga S, Taylor R, Johnston-MacAnanny E. Transfer of IVF-contaminated blastocysts with removal of the zona pellucida resulted in live births. Jrnl of Assisted Reproduction and Genetics. 27 July 2016: 1-4. doi: 10.1007/s10815-016-0776-3.
Yes Su Y, Li JJ, Wang C, Haddad G, Wang WH. Aneuploidy Analysis in Day 7 Human Blastocysts Produced By In Vitro Fertilization. Reproductive Biology and Endocrinology. 2016 April 14; 14 (20): 1-7. doi: 10.1186/s12958-016-0157-x. Open Access Article
Yes Tomita K, Sakai S, Khanmohammadi M, Yamochi T, Hasimoto S, Anzai M, Morimoto Y, Taya M, Hosoi Y. Cryopreservation of a small number of human sperm using enzymatically fabricated, hollow hyaluronan microcapsules handled by conventional ICSI procedures. Journal of Assisted Reproduction and Genetics. 2016 April; 33(4): 501-511. doi: 10.1007/s10815-016-0656-x. Open Access Article
Yes Whitney JB, Schiewe MC, Anderson RE. Single center validation of routine blastocyst biopsy implementation. Journal of Assisted Reproduction and Genetics. 2016 Nov; 33(11): 1507-1513. doi: 10.1007/s10815-016-0792-3. Open Access Article
Yes Yao G, Xu J, Xin Z, Niu W, Shi S, Jin H, Song W, Wang E, Yang Q, Chen L, Sun Y.  Developmental potential of clinically discarded human embryos and associated chromosomal analysis. Scientific Reports; 6(23995): 1-9. doi: 10.1038/srep23995. Open Access Article
Yes Zhang S, Luo K, Cheng D, Tan Y, Lu C, He H, Gu Y, Lu G, Gong F, Lin G. Number of biopsied trophectoderm cells is likely to affect the implantation potential of blastocysts with poor trophectoderm quality. Fertility and Sterility. 2016 Jan 25: 1-10. doi:http://dx.doi.org/10.1016/j.fertnstert.2016.01.011.
Yes Zhan Q, Ye Z, Clarke R, Rosenwalks Z. Zaninovic N. Direct Unequal Cleavages: Embryo Developmental Competence, Genetic Constitution and Clinical Outcome. PLoS ONE. 2016 Dec 1; 11(12):1-19. doi:10.1371/journal.pone.0166398. Open Access Article
Yes Zhu H, Behr B, Reddy V, Hughes M, Yuqiong P, Baker J. Human Embryonic Stem Cell Lines with Lesions in FOXP3 and NF1. Plos One. 2016 March 18. doi:10.1371/journal.pone.0151836. Open Access Article

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Deleye L, Dheedene A, De Coninck D, Sante T, Christodoulou C, Heindryckx B, Van den Abbeel E, De Sutter P, Deforce D, Menten B, Van Nieuwerburgh F. Shallow whole genome sequencing is well suited for the detection of chromosomal aberrations in human blastocysts. Fertil Steril. 2015 Nov;104(5):1276-1285.e1. doi: 10.1016/j.fertnstert.2015.07.1144. Epub 2015 Aug 14. PubMed PMID: 26282994.
Yes

Deng A, Wang WH. Assessment of aneuploidy formation in human blastocysts resulting from cryopreserved donor eggs. Mol Cytogenet. 2015 Feb 15;8:12. doi: 10.1186/s13039-015-0117-8. eCollection 2015. PubMed PMID: 25713597; PubMed Central PMCID: PMC4339107. Open Access Article
No Esh-Broder E, Oron G, Son WY, Holzer H, Tulandi T. Early maternal serum ß-human chorionic gonadotropin (ß-hCG) levels and sex-related growth difference of IVF embryos. J Assist Reprod Genet. 2015 Oct;32(10):1491-5. doi: 10.1007/s10815-015-0550-y. Epub 2015 Aug 25. PubMed PMID: 26304101; PubMed Central PMCID: PMC4615924.
No Giménez C, Sarasa J, Arjona C, Vilamajó E, Martínez-Pasarell O, Wheeler K, Valls G, Garcia-Guixé E, Wells D. Karyomapping allows preimplantation genetic diagnosis of a de-novo deletion undetectable using conventional PGD technology. Reprod Biomed Online. 2015 Sep 8. pii: S1472-6483(15)00429-0. doi: 10.1016/j.rbmo.2015.08.017. [Epub ahead of print] PubMed PMID: 26507283. 
No
Gui B, Yao Z, Huang Y, Mei L, Li Y, Liu D, Liu N, Xia Y, Liang D, Wu L. Morphometric analysis and developmental comparison of embryos from carriers with balanced chromosomal rearrangements in preimplantation genetic diagnosis cycles. Reproduction, Fertility and Development. 2015 June 29; 28 (12): 1953-1963. doi: https://doi.org/10.1071/RD15093
No Haddad G, Deng M, Wang CT, Witz C, Williams D, Griffith J, Skorupski J, Gill J, Wang WH. Assessment of aneuploidy formation in human blastocysts resulting from donated eggs and the necessity of the embryos for aneuploidy screening. J Assist Reprod Genet. 2015 May 9. [Epub ahead of print] PubMed PMID: 25956263 
Yes Lee YS, Park MJ, Park SH, Koo JS, Moon HS, Joo BS. Effect of laser-assisted multi-point zona thinning on development and hatching of cleavage embryos in mice. Clin Exp Reprod Med. 2015 Jun;42(2):51-57. Epub 2015 Jun 30. PubMed PMID: 26161333
No Liebermann J. Vitrification: A Simple and Successful Method for Cryostorage of Human Blastocysts. Cryopreservation and Freeze-Drying Protocols. Methods in Molecular Biology. Eds. Wolkers WF, Oldenhof HR. 2015. 1257: 305-319.
Yes Ruttanajit T, Chanchamroen S, Cram DS, Sawakwongpra K, Suksalak W, Leng X, Fan J, Wang L, Yao Y, Quangkananurug W. Detection and quantitation of chromosomal
mosaicism in human blastocysts using copy number variation sequencing. Prenat Diagn. 2015 Dec 16. doi: 10.1002/pd.4759. [Epub ahead of print] PubMed PMID:26676536. (LYKOS)
No Schiewe MC, Zozula S, Anderson RE, Fahy GM. Validation of microSecure vitrification (µS-VTF) for the effective cryopreservation of human embryos and oocytes. Cryobiology. 2015 Jul 23. pii: S0011-2240(15)00210-2. doi: 10.1016/j.cryobiol.2015.07.009. [Epub ahead of print] PubMed PMID: 26210008.
No Shimoda M, Iwayama H, Ishiyama M, Nakatani A, Yamashita M. Successful Pregnancy by Vitrified–Warmed Embryo Transfer for a Woman with Kallmann Syndrome. Reproductive Medicine and Biology. 2015 July 23; 15 (1): 45-49. doi:10.1007/s12522-015-0214-8.
Yes Whitney JB, Anderson RE, Nugent N, Schiewe MC. Euploidy Predictability of Human Blastocyst Inner Cell Mass and Trophectoderm Grading. Annals of Clinical and Laboratory Research, 2015, Vol 3 No. 1:4.



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Yes Cao S, Zhao C, Zhang J, Wu X, Guo X, Ling X. Retrospective clinical analysis of two artificial shrinkage methods applied prior to blastocyst vitrification on the outcome of frozen embryo transfer. J Assist Reprod Genet. 2014 May;31(5):577-81. doi: 10.1007/s10815-014-0203-6. Epub 2014 Mar 9. PubMed PMID: 24610097; PubMed Central PMCID: PMC4016367
Yes Gliedt D, Goeters S, Saleh W. Embryo Rescue by Placement of Disassembled Day-3 Embryo in Empty Zona Pellucida (ZP) Results in Birth of Normal Female: Case Report. J Clin Embr. 2014 17(1):185-188. Open Access Article
No Guo H, Zhu P, Yan L, Li R, Hu B, Lian Y, Yan J, Ren X, Lin S, Li J, Jin X, Shi X, Liu P, Wang X, Wang W, Wei Y, Li X, Guo F, Wu X, Fan X, Yong J, Wen L, Xie SX, Tang F, Qiao J. The DNA methylation landscape of human early embryos. Nature. 2014 Jul 31;511(7511):606-10. doi: 10.1038/nature13544. Epub 2014 Jul 23. PubMed PMID: 25079557
No Heindryckx B, Neupane J, Vandewoestyne M, Christodoulou C, Jackers Y, Gerris J, Van den Abbeel E, Van Coster R, Deforce D, De Sutter P. Mutation-free baby born from a mitochondrial encephalopathy, lactic acidosis and stroke-like syndrome carrier after blastocyst trophectoderm preimplantation genetic diagnosis. Mitochondrion. 2014 Sep;18:12-7. doi: 10.1016/j.mito.2014.08.005. Epub 2014 Aug 23. PubMed PMID: 25159128
Yes Ishikawa T, Kyoya T, Nakamura Y, Sato E, Tomiyama T, Kyono K. Oxygen consumption rate of early pre-antral follicles from vitrified human ovarian cortical tissue. J Reprod Dev. 2014 Dec 27;60(6):460-7. doi: 10.1262/jrd.2014-009. Epub 2014 Sep 29. PubMed PMID: 25262776; PubMed Central PMCID: PMC4284321.Open Access Article
Yes Kroener LL, Ambartsumyan G, Pisarska MD, Briton-Jones C, Surrey M, Hill D. Increased blastomere number in cleavage-stage embryos is associated with higher aneuploidy. Fertil Steril. 2014 Dec 31. pii: S0015-0282(14)02514-X. doi: 10.1016/j.fertnstert.2014.12.090. [Epub ahead of print] PubMed PMID: 25557243.
No Neupane J, Vandewoestyne M, Heindryckx B, Ghimire S, Lu Y, Qian C, Lierman S, Van Coster R, Gerris J, Deroo T, Deforce D, De Sutter P. A systematic analysis of the suitability of preimplantation genetic diagnosis for mitochondrial diseases in a heteroplasmic mitochondrial mouse model. Hum Reprod. 2014 Feb 12. [Epub ahead of print] PubMed PMID: 24524987.
No Oron G, Sokal-Arnon T, Son WY, Demirtas E, Buckett W, Zeadna A, Holzer H, Tulandi T. Extended embryo culture is not associated with increased adverse obstetric or perinatal outcome. Am J Obstet Gynecol. 2014 Aug;211(2):165.e1-7. doi: 10.1016/j.ajog.2014.03.018. Epub 2014 Mar 12. PubMed PMID: 24631436
Yes Qi ST, Liang LF, Xian YX, Liu JQ, Wang W. Arrested human embryos are more likely to have abnormal chromosomes than developing embryos from women of advanced maternal age. J Ovarian Res. 2014 Jun 13;7:65. doi: 10.1186/1757-2215-7-65. eCollection 2014. PubMed PMID: 24955133; PubMed Central PMCID: PMC4065243. Open Access Article
Yes Tan Y, Yin X, Zhang S, Jiang H, Tan K, Li J, Xiong B, Gong F, Zhang C, Pan X, Chen F, Chen S, Gong C, Lu C, Luo K, Gu Y, Zhang X, Wang W, Xu X, Vajta G, Bolund L, Yang H, Lu G, Du Y, Lin G. Clinical outcome of preimplantation genetic diagnosis and screening using next generation sequencing. GigaScience 2014, 3:30 doi:10.1186/2047-217X-3-30. Published: 4 December 2014. Open Access Article
Yes Taylor TH, Patrick JL, Gitlin SA, Crain JL, Wilson JM, Griffin DK. Blastocyst euploidy and implantation rates in a young (<35 years) and old (≥35 years) presumed fertile and infertile patient population. Fertil Steril. 2014 Aug 22. pii: S0015-0282(14)01834-2. doi: 10.1016/j.fertnstert.2014.07.1207. [Epub ahead of print] PubMed PMID: 25154676.
No Taylor TH, Patrick JL, Gitlin SA, Wilson JM, Crain JL, Griffin DK. Comparison of aneuploidy, pregnancy and live birth rates between day 5 and day 6 blastocysts. Reprod Biomed Online. 2014 Sep;29(3):305-10. doi: 10.1016/j.rbmo.2014.06.001. Epub 2014 Jun 12. PubMed PMID: 25043891
No Taylor TH, Patrick JL, Gitlin SA, Wilson JM, Crain JL, Griffin DK. Outcomes of blastocysts biopsied and vitrified once versus those cryopreserved twice for euploid blastocyst transfer. Reprod Biomed Online. 2014 Jul;29(1):59-64. doi: 10.1016/j.rbmo.2014.03.001. Epub 2014 Mar 15. PubMed PMID: 24794643.
No Tobler KJ, Brezina PR, Benner AT, Du L, Xu X, Kearns WG. Two different microarray technologies for preimplantation genetic diagnosis and screening, due to reciprocal translocation imbalances, demonstrate equivalent euploidy and clinical pregnancy rates. J Assist Reprod Genet. 2014 Apr 26. [Epub ahead of print] PubMed PMID: 24771116.
No Wan CY, Song C, Diao LH, Li GG, Bao ZJ, Hu XD, Zhang HZ, Zeng Y. Laser-assisted hatching improves clinical outcomes of vitrified-warmed blastocysts developed from low-grade cleavage-stage embryos: a prospective randomized study. Reprod Biomed Online. 2014 May;28(5):582-9. doi: 10.1016/j.rbmo.2014.01.006. Epub 2014 Jan 27. PubMed PMID: 24631166
No Xiong B, Tan K, Tan YQ, Gong F, Zhang SP, Lu CF, Luo KL, Lu GX, Lin G. Using SNP array to identify aneuploidy and segmental imbalance in translocation carriers, Genomics Data, 2014 December, 2:92-95
No Yueping Zhang, Saijuan Zhu, Jialong Wu, Suying Liu, Xiaoxi Sun, Quadrivalent asymmetry in reciprocal translocation carriers predicts meiotic segregation patterns in cleavage stage embryos, Reproductive BioMedicine Online, Available online 8 July 2014, ISSN 1472-6483, http://dx.doi.org/10.1016/j.rbmo.2014.06.010.
No Zhang S, Tan K, Gong F, Gu Y, Tan Y, Lu C, Luo K, Lu G, Lin G. Blastocysts can be rebiopsied for preimplantation genetic diagnosis and screening. Fertil Steril. 2014 Dec;102(6):1641-5. doi: 10.1016/j.fertnstert.2014.09.018. Epub 2014 Oct 22. PubMed PMID: 25439805.
No Zhou H, Zao W, Zhang W, Shi J, Shi W. No adverse effects were identified on the perinatal outcomes after laser-assisted hatching treatment. Reprod Biomed Online. 2014 Dec;29(6):692-8. doi: 10.1016/j.rbmo.2014.08.011. Epub 2014 Sep 4. PubMed PMID: 25444502.

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Yes Liang L, Wang CT, Sun X, Liu L, Li M, et al. (2013) Identification of Chromosomal Errors in Human Preimplantation Embryos with Oligonucleotide DNA Microarray. PLoS ONE 8(4): e61838. doi:10.1371/journal.pone.0061838. Open Access Article
No Sheikhi A, Jalali M, Gholamian M, Jafarzadeh A, Jannati S, Mousavifar N. Elimination of apoptotic spermatozoa by magnetic-activated cell sorting improves the fertilization rate of couples treated with ICSI procedure. Andrology. 2013 Oct 2. doi: 10.1111/j.2047-2927.2013.00140.x. [Epub ahead of print] PubMed PMID: 24123893
No Shi W, Zhang S, Zhao W, Xia X, Wang M, Wang H, Bai H, Shi J. Factors related to clinical pregnancy after vitrified-warmed embryo transfer: a retrospective and multivariate logistic regression analysis of 2313 transfer cycles. Hum Reprod. 2013 Apr 18. [Epub ahead of print] PubMed PMID: 23599130.
Yes Tan YQ, Tan K, Zhang SP, Gong F, Cheng DH, Xiong B, Lu CF, Tang XC, Luo KL, Lin G, Lu GX. Single-nucleotide polymorphism microarray-based preimplantation genetic diagnosis is likely to improve the clinical outcome for translocation carriers. Hum Reprod. 2013 Jul 11. [Epub ahead of print] PubMed PMID: 23847111.

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Yes Balakier H, Sojecki A, Motamedi G, Bashar S, Mandel R, Librach C. Is the zona pellucida thickness of human embryos influenced by women's age and hormonal levels? Fertil Steril. 2012 Jul;98(1):77-83. Epub 2012 May 17. PubMed PMID:22608315
Yes Fathi R, Valojerdi MR, Yazdi PE, Ebrahimi B, Alipour H, Hassani F. Development of 4-cell mouse embryos after re-vitrification. Cryobiology. 2012 Feb;64(1):23-6. Epub 2011 Nov 23. PubMed PMID: 22127305
No Hammoud I, Vialard F, Bergere M, Albert M, Gomes DM, Adler M, Malagrida L, Bailly M, Wainer R, Selva J. Follicular fluid protein content (FSH, LH, PG4, E2 and AMH) and polar body aneuploidy. J Assist Reprod Genet. 2012 Aug 14. [Epub ahead of print] PubMed PMID: 22890422.
Yes Hur YS, Park JH, Ryu EK, Yoon HJ, Yoon SH, Hur CY, Lee WD, Lim JH. Effect of artificial shrinkage on clinical outcome in fresh blastocyst transfer cycles. Clin Exp Reprod Med. 2011 Jun;38(2):87-92. Epub 2011 Jun 30. PubMed PMID: 22384424
No Karipcin FS, Moragianni VA, Milette B, Kinzer DR, Thornton KL, Barrett B, Penzias AS. Effect of steroid and antibiotic treatment during assisted hatching on IVF outcomes. Hum Fertil (Camb). 2012 Nov 28. [Epub ahead of print] PubMed PMID: 23190298
Yes Kroener L, Ambartsumyan G, Briton-Jones C, Dumesic D, Surrey M, Munné S, Hill D. The effect of timing of embryonic progression on chromosomal abnormality. Fertil Steril. 2012 Jul 11. [Epub ahead of print] PubMed PMID: 22789142
Yes Li L, Zhang X, Zhao L, Xia X, Wang W. Comparison of DNA apoptosis in mouse and human blastocysts after vitrification and slow freezing. Mol Reprod Dev. 2011 Dec 15. doi: 10.1002/mrd.22018. [Epub ahead of print] PubMed PMID: 22213487.
No Maman E, Geva LL, Yerushalmi G, Baum M, Dor J, Hourvitz A. ICSI increases ongoing pregnancy rates in patients with poor response cycle: multivariate analysis of 2819 cycles. Reproductive biomedicine online 17 September 2012 (Article in Press DOI: 10.1016/j.rbmo.2012.09.003)




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Yes Choi KH, Lee JH, Yang YH, Yoon TK, Lee DR, Lee WS. Efficiency of laser-assisted intracytoplasmic sperm injection in a human assisted reproductive techniques program. Clin Exp Reprod Med. 2011 Sep;38(3):148-152. Open Access Article
Yes Hur YS, Park JH, Ryu EK, Yoon HJ, Yoon SH, Hur CY, Lee WD, Lim JH. Effect of artificial shrinkage on clinical outcome in fresh blastocyst transfer cycles. Clin Exp Reprod Med. 2011 Jun;38(2):87-92. http://dx.doi.org/10.5653/cerm.2011.38.2.87 Open Access Article
Yes Iwayama H, Hochi S, Yamashita M. In vitro and in vivo viability of human blastocysts collapsed by laser pulse or osmotic shock prior to vitrification. J Assist Reprod Genet. 2011 Apr;28(4):355-61. doi: 10.1007/s10815-010-9522-4. Epub 2010 Dec 9. PubMed PMID: 21152966; PubMed Central PMCID: PMC3114962. Open Access Article
No Schoolcraft WB, Janzen JC. “Embryo biopsy: towards trophectoderm isolation and blastocyst analysis.” Human Assisted Reproductive Technology: Future Trends in Laboratory and Clinical Practice. Eds., David Gardner, Botros Rizk, Tommaso Falcone. Cambridge: Cambridge University Press, 2011. 260-268.
Yes Shahine LK, Milki AA, Westphal LM, Baker VL, Behr B, Lathi RB. Day 2 versus day 3 embryo transfer in poor responders: a prospective randomized trial. Fertil Steril. 2011 Jan;95(1):330-2. Epub 2010 Sep 1. PubMed PMID: 20813357
Yes Vandewoestyne M, Heindryckx B, Lepez T, Van Coster R, Gerris J, De Sutter P, Deforce D. Polar body mutation load analysis in a patient with A3243G tRNALeu(UUR) point mutation. Mitochondrion. 2011 Jul;11(4):626-9. Epub 2011 Apr 6. PubMed PMID: 21496500.
Yes Xu X, Duan X, Lu C, Lin G, Lu G. Dynamic distribution of NuMA and microtubules in human fetal fibroblasts, developing oocytes and somatic cell nuclear transferred embryos. Hum Reprod. 2011 Mar 15. [Epub ahead of print] PubMed PMID: 21406448. Open Access Article
Yes Zhu D, Zhang J, Cao S, Zhang J, Heng BC, Huang M, Ling X, Duan T, Tong GQ. Vitrified-warmed blastocyst transfer cycles yield higher pregnancy and implantation rates compared with fresh blastocyst transfer cycles-time for a new embryo transfer strategy? Fertil Steril. 2011 Apr;95(5):1691-5. PubMed PMID: 21315339

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Yes Brezina PR, Benner A, Rechitsky S, Kuliev A, Pomerantseva E, Pauling D, Kearns WG. Single-gene testing combined with single nucleotide polymorphism microarray preimplantation genetic diagnosis for aneuploidy: a novel approach in optimizing pregnancy outcome. Fertil Steril. 2010 Dec 6. [Epub ahead of print] PubMed PMID: 21144509.
Yes Christopikou D, Karamalegos C, Doriza S, Argyrou M, Sisi P, Davies S, Mastrominas M. Spindle and chromosome configurations of human oocytes matured in vitro in two different culture media. Reprod Biomed Online. 2010 May;20(5):639-48. Epub 2010 Feb 10. PubMed PMID: 20347392.
Yes Eaton JL, Hacker MR, Barrett CB, Thornton KL, Penzias AS. Influence of patient age on the association between euploidy and day-3 embryo morphology. Fertil Steril. 2010 Jun;94(1):365-7. Epub 2009 Dec 14. PubMed PMID: 20004892.
Yes Fiorentino F, Kokkali G, Biricik A, Stavrou D, Ismailoglu B, De Palma R, Arizzi L, Harton G, Sessa M, Pantos K. Polymerase chain reaction-based detection of chromosomal imbalances on embryos: the evolution of preimplantation genetic diagnosis for chromosomal translocations. Fertil Steril. Nov;94(6):2001-11, 2011, Epub 2010 Feb 18. PubMed PMID: 20171625.
Yes Fragouli E, Katz-Jaffe M, Alfarawati S, Stevens J, Colls P, Goodall NN, Tormasi S, Gutierrez-Mateo C, Prates R, Schoolcraft WB, Munne S, Wells D. Comprehensive chromosome screening of polar bodies and blastocysts from couples experiencing repeated implantation failure. Fertil Steril. 2010 Aug;94(3):875-87. Epub 2009 Jun 21. PubMed PMID: 19540479
Yes Galán A, Montaner D, Póo ME, Valbuena D, Ruiz V, Aguilar C, Dopazo J, Simón C. Functional genomics of 5- to 8-cell stage human embryos by blastomere single-cell cDNA analysis. PLoS One. 2010 Oct 26;5(10):e13615. PubMed PMID: 21049019; PubMed Central PMCID: PMC2964308. Open Access Article
Yes Hammoud I, Molina-Gomes D, Albert M, Bergere M, Bailly M, Wainer R, Selva J, Vialard F. Are zona pellucida laser drilling and polar body biopsy safe for in vitro matured oocytes? J Assist Reprod Genet. 2010 Jul;27(7):423-7. E pub 2010 May 22. PubMed PMID: 20495883. Open Access Article
Yes Jia Y, Hartshorn C, Hartung O, Wangh LJ. Heat shock memory in preimplantation mouse embryos. Fertil Steril. 2010 May 15;93(8):2760-3. Epub 2010 Apr 7. PubMed PMID: 20378108; PubMed Central PMCID: PMC2873134. Open Access Article
Yes Marquard KL, Stephens SM, Jungheim ES, Ratts VS, Odem RR, Lanzendorf S, Moley KH. Polycystic ovary syndrome and maternal obesity affect oocyte size in in vitro fertilization/intracytoplasmic sperm injection cycles. Fertil Steril. 2010 Nov 10. [Epub ahead of print] PubMed PMID: 21071018.
Yes Miyata H, Matsubayashi H, Fukutomi N, Matsuba J, Koizumi A, Tomiyama T. Relevance of the site of assisted hatching in thawed human blastocysts: a preliminary report. Fertil Steril. 2010 Nov;94(6):2444-7. Epub 2010 Feb 26. PubMed PMID: 20189555.
Yes Parks JC, McCallie BR, Janesch AM, Schoolcraft WB, Katz-Jaffe MG. Blastocyst gene expression correlates with implantation potential. Fertil Steril. 2010 Sep 21. [Epub ahead of print] PubMed PMID: 20864103.
Yes Schoolcraft WB, Fragouli E, Stevens J, Munne S, Katz-Jaffe MG, Wells D. Clinical application of comprehensive chromosomal screening at the blastocyst stage. Fertil Steril. 2010 Oct;94(5):1700-6. Epub 2009 Nov 25. PubMed PMID: 19939370
No Shu Y, Peng W, Zhang J. Pregnancy and live birth following the transfer of vitrified-warmed blastocysts derived from zona- and corona-cell-free oocytes. Reprod Biomed Online. 2010 Oct;21(4):527-32. Epub 2010 May 10. PubMed PMID: 20800550.
Yes Taei A, Gourabi H, Seifinejad A, Totonchi M, Shahbazi E, Valojerdi MR, Eftekhari P, Karimian L, Baharvand H. Derivation of new human embryonic stem cell lines from preimplantation genetic screening and diagnosis-analyzed embryos. In Vitro Cell Dev Biol Anim. 2010 Apr;46(3-4):395-402. Epub 2010 Feb 23. PubMed PMID: 20177993.
Yes Traversa MV, Carey L, Leigh D. A molecular strategy for routine preimplantation genetic diagnosis in both reciprocal and Robertsonian translocation carriers. Mol Hum Reprod. 2010 May;16(5):329-37. Epub 2010 Feb 19. PubMed PMID: 20172975. Open Access Article
Yes Valojerdi MR, Eftekhari-Yazdi P, Karimian L, Hassani F, Movaghar B. Effect of laser zona thinning on vitrified-warmed embryo transfer at the cleavage stage: a prospective, randomized study. Reprod Biomed Online. 2010 Feb;20(2):234-242. Epub 2009 Nov 18. PubMed PMID: 20113961.

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Yes Eaton JL, Hacker MR, Harris D, Thornton KL, Penzias AS. Assessment of day-3 morphology and euploidy for individual chromosomes in embryos that develop to the blastocyst stage. Fertil Steril. 2009 Jun;91(6):2432-6. Epub 2008 Apr 28. PubMed PMID: 18440522.
Yes Feng HL, Hershlag A, Scholl GM, Cohen MA. A retroprospective study comparing three different assisted hatching techniques. Fertil Steril. 2009 Apr;91(4 Suppl):1323-5. Epub 2008 Apr 3. PubMed PMID: 18394610.
Yes Hiraoka K, Hiraoka K, Horiuchi T, Kusuda T, Okano S, Kinutani M, Kinutani K. Impact of the size of zona pellucida thinning area on vitrified-warmed
cleavage-stage embryo transfers: a prospective, randomized study. J Assist Reprod Genet. 2009 Sep-Oct;26(9-10):515-21. Epub 2009 Oct 15. PubMed PMID: 19830543; PubMed Central PMCID: PMC2788686. Open Access Article
Yes Keskintepe L, Agca Y, Sher G, Keskintepe M, Maassarani G. High survival rate of metaphase II human oocytes after first polar body biopsy and vitrification: determining the effect of previtrification conditions. Fertil Steril. 2009 Nov;92(5):1706-15. Epub 2008 Oct 19. PubMed PMID: 18937944.
Yes Krieg SA, Lathi RB, Behr B, Westphal LM. Normal pregnancy after tetraploid karyotype on trophectoderm biopsy. Fertil Steril. 2009 Sep;92(3):1169.e9-1169.e10. Epub 2009 Jul 15. PubMed PMID: 9608167.
Yes Lathi RB, Behr B. Pregnancy after trophectoderm biopsy of frozen-thawed blastocyst. Fertil Steril. 2009 May;91(5):1938-40. Epub 2008 Apr 18. PubMed PMID: 18371958.
Yes Li J, Liu X, Wang H, Zhang S, Liu F, Wang X, Wang Y. Human embryos derived by somatic cell nuclear transfer using an alternative enucleation approach. Cloning Stem Cells. 2009 Mar;11(1):39-50. PubMed PMID: 19196043.
Yes Schoolcraft WB, Katz-Jaffe MG, Stevens J, Rawlins M, Munne S. Preimplantation aneuploidy testing for infertile patients of advanced maternal age: a randomized prospective trial. Fertil Steril. 2009 Jul;92(1):157-62. Epub 2008 Aug 9. PubMed PMID: 18692827
Yes Sertedaki A, Pantos K, Vrettou C, Kokkali G, Christofidou C, Kanavakis E, Dacou-Voutetakis C. Conception and pregnancy outcome in a patient with 11-bp deletion of the steroidogenic acute regulatory protein gene. Fertil Steril. 2009 Mar;91(3):934.e15-8. Epub 2008 Sep 30. PubMed PMID: 18829024.
Yes Sher G, Keskintepe L, Keskintepe M, Maassarani G, Tortoriello D, Brody S. Genetic analysis of human embryos by metaphase comparative genomic hybridization (mCGH) improves efficiency of IVF by increasing embryo implantation rate and reducing multiple pregnancies and spontaneous miscarriages. Fertil Steril. 2009 Dec;92(6):1886-94. Epub 2009 Jan 9. PubMed PMID: 19135663.
Yes Tucker MJ, Ball GD. Assisted hatching as a technique for use in human in vitro fertilization and embryo transfer is long overdue for careful and appropriate study. J Clin Embr. 2009;12:9–14.

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Yes Fathi R, Valojerdi MR, Eftekhari-Yazdi P. Effect of laser-assisted hatching and necrotic blastomere removal on the development of vitrified-warmed four-cell mouse embryos. J Assist Reprod Genet. 2008 Jul;25(7):333-9. Epub 2008 Aug 8. PubMed PMID: 18688708; PubMed Central PMCID: PMC2596673. Open Access Article
Yes Hiraoka K, Fuchiwaki M, Hiraoka K, Horiuchi T, Murakami T, Kinutani M, Kinutani K. Effect of the size of zona pellucida opening by laser assisted hatching on clinical outcome of frozen cleaved embryos that were cultured to blastocyst after thawing in women with multiple implantation failures of embryo transfer: a retrospective study. J Assist Reprod Genet. 2008 Apr;25(4):129-35. PubMed PMID: 18365308; PubMed Central PMCID: PMC2582072. Open Access Article
Yes Jones GM, Cram DS, Song B, Kokkali G, Pantos K, Trounson AO. Novel strategy with potential to identify developmentally competent IVF blastocysts. Hum Reprod. 2008 Aug;23(8):1748-59. Epub 2008 May 13. PubMed PMID: 18477572. Open Access Article
Yes Pangalos CG, Hagnefelt B, Kokkali G, Pantos K, Konialis CP. Birth of a healthy histocompatible sibling following preimplantation genetic diagnosis for chronic granulomatous disease at the blastocyst stage coupled to HLA typing. Fetal Diagn Ther. 2008;24(4):334-9. Epub 2008 Oct 8. PubMed PMID: 18841023.
Yes Turetsky T, Aizenman E, Gil Y, Weinberg N, Shufaro Y, Revel A, Laufer N, Simon A, Abeliovich D, Reubinoff BE. Laser-assisted derivation of human embryonic stem cell lines from IVF embryos after preimplantation genetic diagnosis. Hum Reprod. 2008 Jan;23(1):46-53. Epub 2007 Nov 7. PubMed PMID: 17989069. Open Access Article
Yes Valojerdi MR, Eftekhari-Yazdi P, Karimian L, Ashtiani SK. Effect of laser zona pellucida opening on clinical outcome of assisted reproduction technology in patients with advanced female age, recurrent implantation failure, or frozen-thawed embryos. Fertil Steril. 2008 Jul;90(1):84-91. Epub 2007 Sep 24. PubMed PMID: 17889864.
Yes Wang WH, Kaskar K, Gill J, DeSplinter T. A simplified technique for embryo biopsy for preimplantation genetic diagnosis. Fertil Steril. 2008 Aug;90(2):438-42. Epub 2007 Sep 19. PubMed PMID: 17880956.



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Yes Kokkali G, Traeger-Synodinos J, Vrettou C, Stavrou D, Jones GM, Cram DS, Makrakis E, Trounson AO, Kanavakis E, Pantos K. Blastocyst biopsy versus cleavage stage biopsy and blastocyst transfer for preimplantation genetic diagnosis of beta-thalassaemia: a pilot study. Hum Reprod. 2007 May;22(5):1443-9. Epub 2007 Jan 29. PubMed PMID: 17261575. Open Access Article
Yes Konialis C, Hagnefelt B, Kokkali G, Pantos C, Pangalos C. Pregnancy following preimplantation genetic diagnosis of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). Prenat Diagn. 2007 Nov;27(11):1079-83. PubMed PMID: 17729386.
Yes Lanzendorf SE, Ratts VS, Moley KH, Goldstein JS, Dahan MH, Odem RR. A randomized, prospective study comparing laser-assisted hatching and assisted hatching using acidified medium. Fertil Steril. 2007 Jun;87(6):1450-7. Epub 2007 Jan 4. PubMed PMID: 17207801.
Yes Sagoskin AW, Levy MJ, Tucker MJ, Richter KS, Widra EA. Laser assisted hatching in good prognosis patients undergoing in vitro fertilization-embryo transfer: a randomized controlled trial. Fertil Steril. 2007 Feb;87(2):283-7. Epub 2006 Nov 13. PubMed PMID: 17094975.
Yes Tadir Y, Douglas-Hamilton DH. Laser effects in the manipulation of human eggs and embryos for in vitro fertilization. Methods Cell Biol. 2007;82:409-31. PubMed PMID: 17586266.




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Yes Balaban B, Urman B, Yakin K, Isiklar A. Laser-assisted hatching increases pregnancy and implantation rates in cryopreserved embryos that were allowed to cleave in vitro after thawing: a prospective randomized study. Hum Reprod. 2006 Aug;21(8):2136-40. Epub 2006 Apr 13. PubMed PMID: 16613888. Open Access Article
Yes  Hwu YM, Chen CP, Li SH, Chen PW, Lee RK, Fleming S. Expression of vascular endothelial growth factor messenger ribonucleic acid and protein in human preimplantation embryos. Fertil Steril. 2006 Jun;85(6):1830-2. Epub 2006 Apr 27. PubMed PMID: 16643910.
 Yes Jones AE, Wright G, Kort HI, Straub RJ, Nagy ZP. Comparison of laser-assisted hatching and acidified Tyrode's hatching by evaluation of blastocyst development rates in sibling embryos: a prospective randomized trial. Fertil Steril. 2006 Feb;85(2):487-91. PubMed PMID: 16595232.
 Yes Liebermann J, Tucker MJ. Comparison of vitrification and conventional cryopreservation of day 5 and day 6 blastocysts during clinical application. Fertil Steril. 2006 Jul;86(1):20-6. Epub 2006 Jun 8. PubMed PMID: 16762345.
 Yes Makrakis E, Angeli I, Agapitou K, Pappas K, Dafereras A, Pantos K. Laser versus mechanical assisted hatching: a prospective study of clinical outcomes. Fertil Steril. 2006 Dec;86(6):1596-600. Epub 2006 Oct 20. PubMed PMID: 17055494.
 Yes Mukaida T, Oka C, Goto T, Takahashi K. Artificial shrinkage of blastocoeles using either a micro-needle or a laser pulse prior to the cooling steps of vitrification improves survival rate and pregnancy outcome of vitrified human blastocysts. Hum Reprod. 2006 Dec;21(12):3246-52. Epub 2006 Aug 26. PubMed PMID: 16936299. Open Access Article
 Yes Richter KS, Davis A, Carter J, Greenhouse SJ, Mottla GL, Tucker MJ. No advantage of laser-assisted over conventional intracytoplasmic sperm injection: a randomized controlled trial [NCT00114725]. J Exp Clin Assist Reprod. 2006 Jul 5;3:5. PubMed PMID: 16822317; PubMed Central PMCID: PMC1550249. Open Access Article
 Yes Vialard F, Petit C, Bergere M, Gomes DM, Martel-Petit V, Lombroso R, Ville Y, Gerard H, Selva J. Evidence of a high proportion of premature unbalanced separation of sister chromatids in the first polar bodies of women of advanced age. Hum Reprod. 2006 May;21(5):1172-8. Epub 2006 Jan 12. PubMed PMID: 16410329. Open Access Article

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Yes Hartshorn C, Anshelevich A, Wangh LJ. Laser zona drilling does not induce hsp70i transcription in blastomeres of eight-cell mouse embryos. Fertil Steril. 2005 Nov;84(5):1547-50. PubMed PMID: 16275269.
Yes Hartshorn C, Anshelevich A, Wangh LJ. Rapid, single-tube method for quantitative preparation and analysis of RNA and DNA in samples as small as one cell. BMC Biotechnol. 2005 Jan 13;5:2. PubMed PMID: 15649321; PubMed Central PMCID: PMC546192. Open Access Article
 Yes Kokkali G, Vrettou C, Traeger-Synodinos J, Jones GM, Cram DS, Stavrou D, Trounson AO, Kanavakis E, Pantos K. Birth of a healthy infant following trophectoderm biopsy from blastocysts for PGD of beta-thalassaemia major. Hum Reprod. 2005 Jul;20(7):1855-9. Epub 2005 May 5. PubMed PMID: 15878929. Open Access Article
 Yes McArthur SJ, Leigh D, Marshall JT, de Boer KA, Jansen RP. Pregnancies and live births after trophectoderm biopsy and preimplantation genetic testing of human blastocysts. Fertil Steril. 2005 Dec;84(6):1628-36. PubMed PMID: 16359956.
 Yes Nagy ZP, Taylor T, Elliott T, Massey JB, Kort HI, Shapiro DB. Removal of lysed blastomeres from frozen-thawed embryos improves implantation and pregnancy rates in frozen embryo transfer cycles. Fertil Steril. 2005 Dec;84(6):1606-12. PubMed PMID: 16359953.
Yes Tinney GM, Windt ML, Kruger TF, Lombard CJ. Use of a zona laser treatment system in assisted hatching: optimal laser utilization parameters. Fertil Steril. 2005 Dec;84(6):1737-41. PubMed PMID: 16359974.

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Yes Miller KA, Elkind-Hirsch K, Levy B, Graubert MD, Ross SJ, Scott RT Jr. Pregnancy after cryopreservation of donor oocytes and preimplantation genetic diagnosis of embryos in a patient with ovarian failure. Fertil Steril. 2004 Jul;82(1):211-4. PubMed PMID: 15237014.

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Yes Han TS, Sagoskin AW, Graham JR, Tucker MJ, Liebermann J. Laser-assisted human embryo biopsy on the third day of development for preimplantation genetic diagnosis: two successful case reports. Fertil Steril. 2003 Aug;80(2):453-5. PubMed PMID: 12909515.
Yes Wong BC, Boyd CA, Lanzendorf SE. Randomized controlled study of human zona pellucida dissection using the zona infrared laser optical system: evaluation of blastomere damage, embryo development, and subsequent hatching. Fertil Steril. 2003 Nov;80(5):1249-54. PubMed PMID: 14607583.

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Yes Balaban B, Urman B, Alatas C, Mercan R, Mumcu A, Isiklar A. A comparison of four different techniques of assisted hatching. Hum Reprod. 2002 May;17(5):1239-43. PubMed PMID: 11980745. Open Access Article

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Yes Douglas-Hamilton DH, Conia J. Thermal effects in laser-assisted pre-embryo zona drilling. J Biomed Opt. 2001 Apr;6(2):205-13. PubMed PMID: 11375731.
Yes Douglas-Hamilton DH, Conia JD. Laser-assisted technique aims to improve infertility measures. Biophotonics Int. Sep/Oct 2001

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Yes Douglas-Hamilton DH, Conia JD. Thermal effects in laser-assisted embryo hatching. Proc. SPIE 4065, 260 (2000); doi:10.1117/12.407338