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XYClone is for non-clinical research use only in USA. hESC
research using the XYClone should be conducted in accordance with any
applicable Federal, State or local laws and regulations.
Please Note: The XYClone™ is for use ONLY with ANIMAL and
STEM CELL APPLICATIONS. (For Clinical Laser Assisted Hatching applications,
please see the ZILOS-tk.)
The "Mercury Free"
(pronounced zI-" clOn)
Laser Ablator for Stem Cell
Research, Gene Targeting, Knock Out Mouse Production, SCNT, ICSI, IVF and Assisted Hatching
No other system gives you the ease of use, flexibility and portability
of the XYClone®
An Invaluable Tool for the Researcher
Reliably, quickly, and cleanly opens the zona for stem cell excision
from blastocysts, nuclear transfer, and ICSI. Also, since no
mercury is required, the entire process is safer, for both
you and the embryo.
Choice of Objective Mganification
The XYClone module is available with either the original 40x objective, or a 20x objective. Systems can even be configured to use both!
Plug &
Play
Simply turn on the XYClone and you are ready to go! No warm-up time
is needed.
Save Money on Supplies!
Unlike piezo drills, the XYClone is "non-contact" and requires
no special needles or pipettes. So not only can you achieve your results
quickly and reliably, but you also save money.
Hands-free Laser Firing
When working with micromanipulators, the XYClone allows you to work
in "hands-free" mode by using the optional foot switch to
fire the laser. Simply use the manipulators to position the embryo to
the target and press the foot switch to fire the laser. Your micromanipulation
proceeds rapidly and the time the embryo spends on the microscope stage
is minimized. Also, the laser may be fired as many times as required
to complete the process, without need of reactivating the laser.
Easy
and Fast Zona and Oolemma Ablation
The Flash movie loops below show how easy and fast it is to use the
XYClone for zona ablation. (Requires Flash 6 or higher)
Video footage courtesy of Advanced Cell Technologies. All rights reserved.
Frees Your Microscope Ports - Does Not Interfere with Fluorescence
The extremely compact laser unit (just 42mm x 28mm x 54mm) installs
directly on turret, leaving both the fluorescence and filter cube ports
free for normal use (no removal of components required), and no interference
with normal microscope usage.
Unmatched Portability
For a complete laser system, including software and computer, the
portability of a XYClone laptop configuration can't be beat. All
laser components fit into a custom designed carry case, which offers
both protection and easy transport. Combine this with a laptop unit
and a small digital camera, and you can literally walk out the door
the with a "XYClone To Go!"
Hassle Free Microscope Upgrade or Changeover!!!
The exact same laser configuration installs on ALL brand/model of inverted
microscope, including older models. The XYClone (and ZILOS-tk) are
ONLY complete laser systems available that can be switched from any
brand/model of microscope to any other brand/model of microscope, without
need for customization, laser realignment, and possibly even added cost.
This means that if you buy any different brand/model microscope in the
future, the XYClone can still be used with no changes needed!
