Documentation Header


LASER | CASA | Technology

Laser Articles and Papers

PDF = Portable Document Format. Requires Adobe Acrobat Reader to view. (download reader here)

NEW! Fertility & Sterility: Nov. 2005

"Laser zona drilling does not induce hsp70i transcription in blastomeres of eight-cell mouse embryos." Cristina Hartshorn, Ph.D., Aleksandra Anshelevich, B.S.,
Lawrence J. Wangh, Ph.D.

To assess whether zona drilling with a 1,480-nm laser induces heat shock in eight-cell embryos, we measured hsp70i RNA levels in sets of single blastomeres isolated after laser treatment of mouse embryos that had or had not been heated at 43°C. Unlike heating, laser zona drilling did not stimulate hsp70i expression, even in the blastomeres closest to the laser beam, corroborating the safety of this procedure for assisted reproduction.
(Fertil Steril 2005;84:1547–50. ©2005 by American Society for Reproductive Medicine.)

E-mail us to request a reprint of this article.

Archives

ASRM 2005 Abstracts: XYClone
O-247: A Feeder Cell- and Serum-Free System to harvest Embryonic Stem Cells From Laser Dissected Blastocysts. T. Takeuchi, N. Tanaka, Q.V. Neri, Z. Rosenwaks, G.D. Palermo. Cornell University, New York, NY. (PDF)

Return to Top

ASRM 2005 Abstracts: ZILOS-tk
P-394: A Randomized Blinded Controlled trial on the Effects of Laser Assisted hatching on the Outcome of IVF Cycles in Women Under 38 ears of Age. C.L. Librach, et. al. (PDF)
P-507: Preimplantation Embryo Aneuploidy rates in Couples Undergoing Donor Egg In Virto Fertilization Cycles. W.G. Kearns, et. al. (PDF)
P-525: Correlating Cleavge Stage Embryo Quality with Clinical Outcome Following In Vitro Fertilization (IVF) with Preimplantation Geneitc Diagnosis (PGD) and Single Embryo Transfer (SET). W.G. Kearns, et. al. (PDF)
P-603: Effect of Laser Assisted Hatching on Pregnancy Rates on Patients Undergoing Assisted Reproduction. S.B. Hudson, et. al. (PDF)
P-624: Laser Biopsy of Day 3 Embryos Yields Higher Implantation Rate Than Biopsy with Acidic Tyrodes. J. Stevens, et. al. (PDF)

Return to Top

ASRM 2004 Abstracts: ZILOS-tk
O-59: Laser-assisted hatching of intact and blastomere-ablated murine embryos. R.E. Fothergill, T.J. Kuehl. (PDF)
O-241: Does length of ovarian stimulation affect IVF pregnancy and implantation rates? M.P. Portmann, et. al. (PDF)
P-301: Comparison of embryo development between non-biopsy cycles and laser assisted biopsy cycles for preimplantation genetic diagnosis (PGD) within the same patient population. J. Carter, et. al. (PDF)
P-304: Embryo development from day 3 to day 5 after laser assisted blastomere biopsy for preimplantation genetic diagnosis (PDG), relative to day 3 embryo quality. M. Moyer, et. al. (PDF)
P-311: Preimplantation genetic diagnosis for Duchenne muscular dystrophy.
M. Malcov, et. al. (PDF) Note: The PDF version of the abstract does not mention the ZILOS, yet the presented poster does - see Poster Image.
P-312: Accuracy of morphologic assessment of blastocysts in selecting genetically normal embryos. D. Dasig, et. al. (PDF) Note: ZILOS-tk was not mentioned but was used in protocol.
P-326: Comaprison of computer assisted infrared laser with acid tyrode solution in zona drilling for embryo biopsy. M. Li, et. al. (PDF)
P-360: A randomized, prospective study comparing laser assisted hatching and assisted hatching using acidified medium. S. E. Lanzendorf. (PDF)
P-361: Preliminary results of a prospective randomized study comaring the fertilization outcome and preimplantation embryo development between conventional and laser assisted intracytoplasmic sperm injection (ICSI). A. Davis, et. al. (PDF)
P-547: Comparison of assisted hatching using chemical vs. laser methods. W.A. Caswell, et. al. (PDF)
P-550: Does laser assisted hatching of residual embryos on day 3 affect blastocyst development? M.P. Portman, et. al. (PDF, View Actual Poster)

ASRM 2003 Abstracts - ZILOS Laser

ASRM 2003 Abstracts: ZILOS
Six abstracts (one oral presentation and five poster presentations) featuring the ZILOS were accepted for the 2003 ASRM meeting in San Anotnio TX. Read all six here! (PDF) 

ZILOS Journal References - Partial List

Journal Reference
Jones AE, Wright G, Kort HI, Straub RJ, Nagy ZP. Comparison of laser-assisted hatching and acidified Tyrode’s hatching by evaluation of blastocyst development rates in sibling embryos: a prospective randomized trial. Fertil Steril. 2006. Feb; 85(2):487-491. (Full Article)
Miller KA, Elkind-Hirsch K, Levy B, Graubert MD, Ross SJ, Scott RT Jr. Pregnancy after cryopreservation of donor oocytes and preimplantation genetic diagnosis of embryos in a patient with ovarian failure. Fertil Steril. 2004 Jul;82(1):211-4.
Han TS, Sagoskin AW, Graham JR, Tucker MJ, Liebermann J. Laser-assisted human embryo biopsy on the third day of development for preimplantation genetic diagnosis: two successful case reports.
Fertil Steril. 2003 Aug;80(2):453-5.
Ali J, Rahbar S, Burjaq H, Sultan AM, Al Flamerzi M, Shahata MA. Routine laser assisted hatching results in significantly increased clincal pregnancies.
J Assist Reprod Genet. 2003 May;20(5):177-81.
Wong BC, Boyd CA, Lanzendorf SE. Randomized controlled study of human zona pellucida dissection using the zona infrared laser optical system: evaluation of blastomere damage, embryo development, and subsequent hatching.
Fertil Steril. 2003 Nov;80(5):1249-54.
Laser-assisted technique aims to improve fertility measures. Biophotonics, Sept/Oct. 2001. (PDF)

Return to Top