XYClone is for non-clinical research use only.hESC research using the XYClone should be conducted in accordance with any applicable Federal, State or local laws and regulations.
Please Note: The XYClone is for use ONLY with ANIMAL and STEM CELL APPLICATIONS. (For Clinical Laser Assisted Hatching and Biopsy applications, please see the ZILOS-tk.)
XYClone for Laser-assisted Hatching
Download Bovine LAH Sell Sheet
"We perform on farm embryo collection and transfer. We travel almost 75K miles a year and setup in the clients' barn or house. The microscope and laser system is packed in a travel case and setup every day. Once the system is setup, calibrated, and targeted, I have not had to adjust it again. We work in some very dusty and dirty places and I have not had one problem with the system. In addition, the clients greatly enjoy being able to see their embryos before transfer and they can watch the computer screen without disrupting the embryologist." Michael Werhman, Ph.D., Rocky Mountain Reproductive Service
NEW FROM IETS 2008 - Jan 6-8, 2008
Utilization of Laser Assisted Hatching to Improve the Pregnancy Rate of In Vitro Fertilized Bovine Embryos (Download Poster - Download Full Thesis)
S. MengesA, H. WeiB, D. FaberB, D. KraemerA, and C. LongA
ADepartment of Veterinary Physiology and Pharmacology, Texas A&M University, College Station, TX 77843, USA, BTransova Genetics, Sioux Center, IA 51250, USA
"These results demonstrate that laser assisted hatching using the XYClone system does not inhibit in vitro embryo viability and development. A significant difference was found in the 60 day pregnancy rate between control and cut embryos. This difference exhibits a large potential for this system to improve 60 day pregnancy rates of in-vitro produced embryos."
The Effect of Lipid Segregation with or without Zona Pellucida Laser Drilling on Post Thaw Embryo Development of In Vitro Produced Bovine Embryos (Download Poster)
J.H. Pryor1, C.R. Looney1, S. Romo2, D.C. Kraemer3and C.R. Long3
1Ovagenix, Bryan, TX 77805; 2Facultad de Estudios Superiores Cuautitlan, UNAM, Mexico; 3Texas A&M University, Department of Veterinary Physiology and Pharmacology, College Station, TX 77843
The objective of this study was to determine if lipid segregation with or without zona pellucida cutting on post thawed in vitro produced bovine embryos would effect survivability and development.
CBCFLAH and LAH exhibited a significantly greater number of both total and live cells than Control (P<0.05)
Increased Pregnancy Rate for Bovine Embryos
In an unpublished study, a 20% increase in pregnancy rate occurred when the XYClone was used for laser assisted hatching of bovine embryos.
Image below shows frozen / thawed bovine embryos before and after laser assisted hatching (courtesy of Michael E. Wehrman, Ph.D., Rocky Mountain Reproductive Services)